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SDS-PAGE

FABP6 / I-BABP recombinant protein

Recombinant Human FABP6 / I-BABP Protein

Gene Names
FABP6; ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB
Purity
> 98 % as determined by SDS-PAGE
Synonyms
FABP6 / I-BABP; Recombinant Human FABP6 / I-BABP Protein; I-15P; I-BABP; I-BALB; I-BAP; ILBP; ILBP3; ILLBP; FABP6 / I-BABP recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 98 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.5
Sequence Length
128
Application Notes
The recombinant human FABP6 consisting of 128 amino acids and has a calculated molecular mass of 14.4 kDa as estimated in SDS-PAGE under reducing conditions.
Predicted N Terminal
Met 1
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for FABP6 / I-BABP recombinant protein
Background: Gastrotropin, also known as Fatty acid-binding protein 6, Ileal lipid-binding protein, ILBP, Intestinal 15 kDa protein, Intestinal bile acid-binding protein, I-BABP and FABP6, is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. Isoform 2 of FABP6 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 of FABP6 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. FABP6 / I-BABP is a cancer-related protein that acts as an intracellular transporter of bile acid in the ileal epithelium. FABP6 / I-BABP may also play an important role in early carcinogenesis.

Description: A DNA sequence encoding the human FABP6 (AAH22489.1) (Met 1-Ala 128) was expressed and purified.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
19,874 Da
NCBI Official Full Name
FABP6 protein
NCBI Official Synonym Full Names
fatty acid binding protein 6
NCBI Official Symbol
FABP6
NCBI Official Synonym Symbols
ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB
NCBI Protein Information
gastrotropin
UniProt Protein Name
Gastrotropin
UniProt Gene Name
FABP6
UniProt Synonym Gene Names
ILBP; ILLBP; GT; ILBP; I-15P; I-BABP

NCBI Description

This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

FABP6: Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. 2 isoforms of the human protein are produced by alternative promoter.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 5q33.3

Cellular Component: cytoplasm; cytosol

Molecular Function: lipid binding

Biological Process: bile acid and bile salt transport; negative regulation of cell proliferation; triacylglycerol catabolic process

Research Articles on FABP6 / I-BABP

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Product Notes

The FABP6 / I-BABP fabp6 (Catalog #AAA2545481) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The recombinant human FABP6 consisting of 128 amino acids and has a calculated molecular mass of 14.4 kDa as estimated in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the FABP6 / I-BABP fabp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FABP6 / I-BABP, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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