FABP6 recombinant protein

FABP6 Protein, Human, Recombinant

Cat. Num. AAA8121193

• Gene Names: FABP6; ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB
• Purity: >98% as determined by SDS-PAGE
• Synonyms: FABP6; FABP6 Protein; Human; Recombinant; Human FABP6/I-BABP Protein; I-15P Protein; I-BABP Protein; I-BALB Protein; I-BAP Protein; ILBP Protein; ILBP3 Protein; ILLBP Protein; fatty acid binding protein 6; ileal; FABP6 recombinant protein

• Host: E Coli
• Purity/Purification: >98% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.5. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Ala128

• Species: Human
• Predicted N Terminal: Met 1
• Tag: Native
• Protein Construction: A DNA sequence encoding the human FABP6 (AAH22489.1)(Met 1-Ala 128) was expressed and purified.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

Related Product Information for FABP6 recombinant protein

Background: Gastrotropin, also known as Fatty acid-binding protein 6, Ileal lipid-binding protein, ILBP, Intestinal 15kDa protein, Intestinal bile acid-binding protein, I-BABP and FABP6, is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Isoform2 of FABP6 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform1of FABP6 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform2is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. FABP6/I-BABP is a cancer-related protein that acts as an intracellular transporter of bile acid in the ileal epithelium. FABP6/I-BABP may also play an important role in early carcinogenesis.

References

Kurz M., et al., 2003, Proteins 50:312-328. Ohmachi,T. et al., 2006, Clin Cancer Res.12 (17):5090-5. Fang C., et al., 2007, Cancer Res. 67:9039-9046. Szczerbal,I. et al., 2007, Cytogenet Genome Res.118 (1):63-6.

NCBI and Uniprot Product Information

• NCBI GI #: 18490679
• NCBI GeneID: 2172
• Molecular Weight: 19,874 Da
• NCBI Official Full Name: FABP6 protein
• NCBI Official Synonym Full Names: fatty acid binding protein 6
• NCBI Official Symbol: FABP6
• NCBI Official Synonym Symbols: ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB
• NCBI Protein Information: gastrotropin
• Protein Family: Gastrotropin

NCBI Description

This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008]