Typical Testing Data
Mouse Estrogen Receptor Beta ELISA Kit | ERbeta elisa kit
Mouse Estrogen Receptor Beta ELISA Kit
Typical Testing Data
Typical Testing Data
Typical Standard Curve
Typical Standard Curve
NCBI and Uniprot Product Information
Uniprot Description
ER-beta: a nuclear hormone receptor and transcription factor. Binds and activated by estrogen. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Eight alternatively-spliced isoforms have been described. Isoform beta-cx lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability.
Protein type: DNA-binding; Nuclear receptor
Cellular Component: cell soma; cilium; cytoplasm; mitochondrion; neuron projection; nucleus; perikaryon; perinuclear region of cytoplasm; plasma membrane
Molecular Function: DNA binding; drug binding; enzyme binding; estrogen receptor activity; estrogen response element binding; hormone binding; lipid binding; metal ion binding; peroxisome proliferator activated receptor binding; protein binding; sequence-specific DNA binding; steroid binding; steroid hormone receptor activity; transcription factor activity; zinc ion binding
Biological Process: behavioral fear response; brain development; estrogen receptor signaling pathway; induction of apoptosis by hormones; learning and/or memory; negative regulation of behavior; negative regulation of cell proliferation; negative regulation of epithelial cell proliferation; negative regulation of smooth muscle cell proliferation; negative regulation of transcription from RNA polymerase II promoter; neuron migration; ovarian follicle development; positive regulation of apoptosis; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of vasodilation; regulation of cell proliferation; regulation of neuron apoptosis; regulation of transcription, DNA-dependent; response to testosterone stimulus; Sertoli cell proliferation; steroid hormone mediated signaling; steroid hormone receptor signaling pathway; transcription from RNA polymerase II promoter; transcription, DNA-dependent; uterus development; vagina development
Research Articles on ERbeta
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Product Notes
The Mouse ERbeta esr2 (Catalog #AAA765014) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA765014 ELISA Kit recognizes Mouse ERbeta. It is sometimes possible for the material contained within the vial of "Estrogen Receptor Beta, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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