Stem Cell Growth Factor alpha Active Protein
Stem Cell Growth Factor alpha, Recombinant, Human (SCGFa)
Purity
Molecular Biology Grade98% (SDS-PAGE, HPLC)
Synonyms
Stem Cell Growth Factor alpha; Recombinant; Human (SCGFa); Stem Cell Growth Factor alpha active protein
Host
E Coli
Purity/Purification
Molecular Biology Grade
98% (SDS-PAGE, HPLC)
98% (SDS-PAGE, HPLC)
Form/Format
Supplied as a lyophilized powder. Reconstitute with sterile ddH2O, carrier protein. DO NOT VORTEX
Biological Activity
Determined by its inhibitory effect on the proliferation of TF-1 cells previously grown in media containing GM-CSF. The ED50 for this effect was observed at 2.5 ng/ml.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O, carrier protein. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for Stem Cell Growth Factor alpha active protein
Stem Cell Growth Factor alpha (SCGF-alpha)is a newly discovered hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. Human SCGF-alpha is a non-glycosylated 33.9kD species-specific cytokine that can support growth of primitive hematopoietic cells, and in combination of EPO or GM-CSF, it promotes proliferation of erythroid and myeloid progenitors, respectively.
Product Categories/Family for Stem Cell Growth Factor alpha active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
Stem cell growth factor-alpha
Uniprot Description
CLEC11A: Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 19q13.3
Cellular Component: extracellular space; cytoplasm; extracellular region
Molecular Function: growth factor activity; carbohydrate binding
Biological Process: positive regulation of cell proliferation
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Product Notes
The Stem Cell Growth Factor alpha (Catalog #AAA650262) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Stem Cell Growth Factor alpha, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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