Human cytotoxic and regulatory T cell molecule ELISA Kit | CRTAM elisa kit
Human Cytotoxic and regulatory T-cell molecule, CRTAM ELISA Kit
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
NCBI and Uniprot Product Information
NCBI Description
The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 [PubMed 18329370]).[supplied by OMIM, Feb 2009]
Uniprot Description
CRTAM: Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. Belongs to the nectin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q24.1
Cellular Component: plasma membrane; integral to membrane
Molecular Function: receptor binding
Biological Process: regulation of immune response; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; detection of tumor cell; activated T cell proliferation; detection of stimulus; cell recognition; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of cytokine secretion; T cell mediated cytotoxicity
Research Articles on CRTAM
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Product Notes
The Human CRTAM crtam (Catalog #AAA925630) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA925630 ELISA Kit recognizes Human CRTAM. It is sometimes possible for the material contained within the vial of "cytotoxic and regulatory T cell molecule, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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