Human carnitine palmitoyltransferase 1A (liver) ELISA Kit | CPT1A elisa kit
Human Carnitine O-palmitoyltransferase 1, liver isoform, CPT1A/CPT1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism.
Catalytic activity: Palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.2 PublicationsManual assertion based on experiment in:Ref.11
Enzyme regulation: Inhibited by malonyl-CoA.1 PublicationManual assertion based on experiment in:Ref.13
Research Articles on CPT1A
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Product Notes
The Human CPT1A cpt1a (Catalog #AAA9332032) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9332032 ELISA Kit recognizes Human CPT1A. It is sometimes possible for the material contained within the vial of "carnitine palmitoyltransferase 1A (liver), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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