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SDS-Page (Figure. SDS-PAGE)

Superoxide Dismutase 3, Extracellular Protein | SOD3 protein

Eukaryotic Superoxide Dismutase 3, Extracellular (SOD3)

Gene Names
SOD3; EC-SOD
Applications
SDS-Page, Western Blot
Purity
>97%
Synonyms
Superoxide Dismutase 3; Extracellular; Eukaryotic Superoxide Dismutase 3; Extracellular (SOD3); SOD-3; EC-SOD; Extracellular Superoxide Dismutase Cu-Zn; SOD3 protein
Ordering
For Research Use Only!
Host
CHO Cell
Purity/Purification
>97%
Form/Format
Freeze-dried powder
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Sequence Positions
Trp19~Ala240
Sequence Length
240
Applicable Applications for SOD3 protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Source
Eukaryotic expression
Species
Human
Tag
N-terminal His Tag
Subcellular Location
Secreted
Isoelectric Point
6.8
Reconstitution
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Preparation and Storage
Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

(Figure. SDS-PAGE)

SDS-Page (Figure. SDS-PAGE)

Gene Sequencing

(Figure. Gene Sequencing (Extract))

Gene Sequencing (Figure. Gene Sequencing (Extract))
Product Categories/Family for SOD3 protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Predicted Molecular Mass: 25.8kDa
Accurate Molecular Mass: 30kDa
NCBI Official Full Name
Extracellular superoxide dismutase
NCBI Official Synonym Full Names
superoxide dismutase 3
NCBI Official Symbol
SOD3
NCBI Official Synonym Symbols
EC-SOD
NCBI Protein Information
extracellular superoxide dismutase [Cu-Zn]
UniProt Protein Name
Extracellular superoxide dismutase [Cu-Zn]
UniProt Gene Name
SOD3
UniProt Synonym Gene Names
EC-SOD
UniProt Entry Name
SODE_HUMAN

NCBI Description

This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk. [provided by RefSeq, Oct 2015]

Uniprot Description

SOD3: Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. Belongs to the Cu-Zn superoxide dismutase family.

Protein type: EC 1.15.1.1; Secreted, signal peptide; Oxidoreductase; Secreted

Chromosomal Location of Human Ortholog: 4p15.2

Cellular Component: extracellular matrix; extracellular space; Golgi lumen; cytoplasm; extracellular region; trans-Golgi network; nucleus

Molecular Function: heparin binding; protein binding; copper ion binding; zinc ion binding; superoxide dismutase activity

Biological Process: response to reactive oxygen species; response to copper ion; removal of superoxide radicals; response to hypoxia

Research Articles on SOD3

Similar Products

Product Notes

The SOD3 sod3 (Catalog #AAA2122435) is a Protein produced from CHO Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Trp19~Ala240. AAA Biotech's Superoxide Dismutase 3, Extracellular can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the SOD3 sod3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Superoxide Dismutase 3, Extracellular, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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