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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using GINS1 Polyclonal Antibody at dilution 1:25)

Rabbit GINS1 Polyclonal Antibody | anti-GINS1 antibody

GINS1 Polyclonal Antibody

Gene Names
GINS1; PSF1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
GINS1; Polyclonal Antibody; GINS1 Polyclonal Antibody; PSF1; RP4-691N24.2; anti-GINS1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2.3mg/mL (varies by lot)
Sequence Length
196
Applicable Applications for anti-GINS1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:25-1:100
Immunogen
Synthetic peptide of human GINS1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using GINS1 Polyclonal Antibody at dilution 1:25)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using GINS1 Polyclonal Antibody at dilution 1:25)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using GINS1 Polyclonal Antibody at dilution 1:25)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using GINS1 Polyclonal Antibody at dilution 1:25)
Related Product Information for anti-GINS1 antibody
DNA replication complex GINS protein PSF1 is a protein that in humans is encoded by the GINS1 gene. The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. GINS1 is essential for function. Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. Forms a stable subcomplex with GINS4. GINS complex interacts with DNA primase in vitro.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
22,988 Da
NCBI Official Full Name
GINS1 protein
NCBI Official Synonym Full Names
GINS complex subunit 1 (Psf1 homolog)
NCBI Official Symbol
GINS1
NCBI Official Synonym Symbols
PSF1
NCBI Protein Information
DNA replication complex GINS protein PSF1; partner of sld five-1
UniProt Protein Name
DNA replication complex GINS protein PSF1
UniProt Gene Name
GINS1
UniProt Synonym Gene Names
KIAA0186; PSF1
UniProt Entry Name
PSF1_HUMAN

NCBI Description

The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1, Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]).[supplied by OMIM, Mar 2008]

Uniprot Description

GINS1: The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single- stranded DNA. GINS1 is essential for function. Belongs to the GINS1/PSF1 family.

Protein type: Motility/polarity/chemotaxis; DNA replication

Chromosomal Location of Human Ortholog: 20p11.21

Cellular Component: nucleoplasm; cytoplasm; nucleus

Biological Process: DNA strand elongation during DNA replication; mitotic cell cycle; inner cell mass cell proliferation

Research Articles on GINS1

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Product Notes

The GINS1 gins1 (Catalog #AAA2516875) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GINS1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GINS1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:25-1:100. Researchers should empirically determine the suitability of the GINS1 gins1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GINS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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