FCRL2 cdna clone
FCRL2 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Apr 2009]
Uniprot Description
FCRL2: May have an regulatory role in normal and neoplastic B cell development. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q21
Molecular Function: protein binding; SH3/SH2 adaptor activity
Research Articles on FCRL2
Similar Products
Product Notes
The FCRL2 fcrl2 (Catalog #AAA1273775) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGTGGGAAT GGAAAATATG CAACAGCCAT GGGGCCAGGC CCTTTGCTGA GCCTGCAGGT TGGGAGTTTG TGAATCTATT GAGGCATCAC AAATCTTTTC TGATAGCCCC TCTGTGTCTG TCAGTTCCAG TGTCTCGCCC TGTCCTCACC CTCAGGTCTC CTGGGGCCCA GGCTGCAGTG GGGGACCTGC TGGAGCTTCA CTGTGAGGCC CTGAGAGGCT CTCCCCCAAT CTTGTACCAA TTTTATCATG AGGATGTCAC CCTTGGGAAC AGCTCGGCCC CCTCTGGAGG AGGGGCCTCC TTCAACCTCT CTTTGACTGC AGAACATTCT GGAAACTACT CCTGTGAGGC CAACAACGGC CTGGGGGCCC AGTGCAGTGA GGCAGTGCCA GTCTCCATCT CAGGACCTGA TGGCTATAGA AGAGACCTCA TGACAGCTGG AGTTCTCTGG GGACTGTTTG GTGTCCTTGG TTTCACTGGT GTTGCTTTGC TGTTGTATGC CTTGTTCCAC AAGATATCAG GAGAAAGTTC TGCCACTAAT GAACCCAGAG GGGCTTCCAG GCCAAATCCT CAAGAGTTCA CCTATTCAAG CCCAACCCCA GACATGGAGG AGCTGCAGCC AGTGTATGTC AATGTGGGCT CTGTAGATGT GGATGTGGTT TATTCTCAGG TCTGGAGCAT GCAGCAGCCA GAAAGCTCAG CAAACATCAG GACACTTCTG GAGAACAAGG ACTCCCAAGT CATCTACTCT TCTGTGAAGA AATCATAA. It is sometimes possible for the material contained within the vial of "FCRL2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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