FCRL2 recombinant protein

FCRL2 Protein, Human, Recombinant (His Tag)

Cat. Num. AAA8122004

• Gene Names: FCRL2; FCRH2; IFGP4; IRTA4; SPAP1; CD307b; SPAP1A; SPAP1B; SPAP1C
• Purity: >90% as determined by SDS-PAGE
• Synonyms: FCRL2; FCRL2 Protein; Human; Recombinant (His Tag); Human FCRL2/FCRH2 Protein (His Tag); CD307b Protein; FCRH2 Protein; IFGP4 Protein; IRTA4 Protein; SPAP1 Protein; SPAP1A Protein; SPAP1B Protein; SPAP1C Protein; Fc receptor like 2; FCRL2 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Asp395

• Species: Human
• Endotoxin: <1.0EU per ug protein as determined by the LAL method.
• Predicted N Terminal: Leu 20
• Tag: C-His
• Protein Construction: A DNA sequence encoding the human FCRL2 (NP_110391.2)(Met1-Asp395) was expressed with a polyhistidine tag at the C-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

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Related Product Information for FCRL2 recombinant protein

Background: Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 has robust predictive value for determining IGHV gene mutation status and clinical progression and thus may further improve prognostic definition in CLL (B-cell chronic lymphocytic leukemia).

NCBI and Uniprot Product Information

• NCBI GI #: 19923629
• NCBI GeneID: 79368
• NCBI Accession #: NP_110391.2
• NCBI GenBank Nucleotide #: NM_030764.3
• Molecular Weight: 22,533 Da
• NCBI Official Full Name: Fc receptor-like protein 2 isoform 1
• NCBI Official Synonym Full Names: Fc receptor like 2
• NCBI Official Symbol: FCRL2
• NCBI Official Synonym Symbols: FCRH2; IFGP4; IRTA4; SPAP1; CD307b; SPAP1A; SPAP1B; SPAP1C
• NCBI Protein Information: Fc receptor-like protein 2
• Protein Family: Fc receptor-like protein

NCBI Description

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Apr 2009]