SDS-PAGE
CD59a / Protectin / MAC-IP Recombinant Protein | CD59a recombinant protein
Recombinant Mouse CD59a / Protectin / MAC-IP Protein (His tag)
Gene Names
Cd72; CD72c; Ly-19; Ly-32; Lyb-2; Ly-m19
Purity
> 92 % as determined by SDS-PAGE
Synonyms
CD59a / Protectin / MAC-IP; Recombinant Mouse CD59a / Protectin / MAC-IP Protein (His tag); RP24-297H17.1; AA987121; Cd59; protectin; CD59a recombinant protein
Host
Human Cells
Purity/Purification
> 92 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
354
Application Notes
The secreted recombinant mouse CD59a comprises 83 amino acids and has a calculated molecular mass of 9.7 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 18 kDa band in SDS-PAGE under reducing conditions.
Predicted N Terminal
Leu 24
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for CD59a recombinant protein
Background: Protectin, a complement regulatory protein, also known as CD59, or MIRL (membrane inhibitor of reactive lysis) is a small protein that inhibits the complement membrane attack complex by binding C5b678 and preventing C9 from binding and polymerizing. The amino-terminal 25 amino acids represented a typical signal peptide sequence and the carboxy-terminal hydrophobic amino acids were characteristic for phosphatidylinositol-anchored proteins.It was found that the CD59/Protectin antigen is a small protein sometimes associated with larger components (45 and 80 kD) in urine. CD59/Protectin antigen was released from the surface of transfected COS cells by phosphatidylinositol-specific phospholipase C, demonstrating that it is attached to the cell membrane by means of a glycolipid anchor; it is therefore likely to be absent from the surface of affected erythrocytes in the disease paroxysmal nocturnal hemoglobinuria.
Description: A DNA sequence encoding the mouse CD59a (NP_031680.2) (Met 1-Lys 95), without the pro peptide, was fused with a C-terminal polyhistidine tag.
Description: A DNA sequence encoding the mouse CD59a (NP_031680.2) (Met 1-Lys 95), without the pro peptide, was fused with a C-terminal polyhistidine tag.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40,347 Da
NCBI Official Full Name
B-cell differentiation antigen CD72 isoform 2
NCBI Official Synonym Full Names
CD72 antigen
NCBI Official Symbol
Cd72
NCBI Official Synonym Symbols
CD72c; Ly-19; Ly-32; Lyb-2; Ly-m19
NCBI Protein Information
B-cell differentiation antigen CD72
UniProt Protein Name
B-cell differentiation antigen CD72
Protein Family
UniProt Gene Name
Cd72
UniProt Synonym Gene Names
Ly-32; Ly32; Lyb-2; Ly-32
Uniprot Description
CD72: Plays a role in B-cell proliferation and differentiation.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 4 A5|4 23.04 cM
Cellular Component: integral to plasma membrane
Research Articles on CD59a
Similar Products
Product Notes
The CD59a cd72 (Catalog #AAA2546823) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The secreted recombinant mouse CD59a comprises 83 amino acids and has a calculated molecular mass of 9.7 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 18 kDa band in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the CD59a cd72 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD59a / Protectin / MAC-IP, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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