SDS-PAGE
CD200R1 / OX-2R recombinant protein
Recombinant Mouse CD200R1 / OX-2R Protein (His tag)
Gene Names
Cd200r1; OX2R; Mox2r; CD200R
Purity
> 90 % as determined by SDS-PAGE
Synonyms
CD200R1 / OX-2R; Recombinant Mouse CD200R1 / OX-2R Protein (His tag); CD200R; Mox2r; OX2R; CD200R1 / OX-2R recombinant protein
Host
Human Cells
Purity/Purification
> 90 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
326
Application Notes
The recombinant mouse CD200R1 consists of 224 amino acids after removal of the signal peptide and has a predicted molecular mass of 24.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmCD200R1 is approximately 55-65 kDa due to glycosylation.
Predicted N Terminal
Thr 21
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for CD200R1 / OX-2R recombinant protein
Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cell surface glycoprotein CD200 receptor 1 (CD200R1) is an isoform of CD200 receptors which is expressed on cells of the myeloid lineage. CD200R1 is a receptor for the OX-2 membrane glycoprotein. The receptor-substrate interaction may serve as a myeloid downregulatory signal.
Description: A DNA sequence encoding the extracellular domain (Met 1-Pro 238) of mouse CD200R1 (NP_067300.1) was expressed, with a C-terminal polyhistidine tag.
Description: A DNA sequence encoding the extracellular domain (Met 1-Pro 238) of mouse CD200R1 (NP_067300.1) was expressed, with a C-terminal polyhistidine tag.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,505 Da
NCBI Official Full Name
cell surface glycoprotein CD200 receptor 1
NCBI Official Synonym Full Names
CD200 receptor 1
NCBI Official Symbol
Cd200r1
NCBI Official Synonym Symbols
OX2R; Mox2r; CD200R
NCBI Protein Information
cell surface glycoprotein CD200 receptor 1
UniProt Protein Name
Cell surface glycoprotein CD200 receptor 1
UniProt Gene Name
Cd200r1
UniProt Synonym Gene Names
Mox2r; Ox2r
Uniprot Description
CD200R: Receptor for the CD200/OX2 cell surface glycoprotein. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. Belongs to the CD200R family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 16|16 B4
Cellular Component: external side of plasma membrane; receptor complex
Molecular Function: protein binding; receptor activity
Research Articles on CD200R1 / OX-2R
Similar Products
Product Notes
The CD200R1 / OX-2R cd200r1 (Catalog #AAA2547099) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse CD200R1 consists of 224 amino acids after removal of the signal peptide and has a predicted molecular mass of 24.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmCD200R1 is approximately 55-65 kDa due to glycosylation. Researchers should empirically determine the suitability of the CD200R1 / OX-2R cd200r1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD200R1 / OX-2R, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
