Testing Data
(Jurkat cell lysate was probed with MBS602894 at 0.5ug/ml. Proteins were visualized using an IgG (HRP) goat anti-mouse and a chemiluminescence detection system. Arrow indicates Histone H1 + core proteins (~14-33kD).)
Mouse Histones Monoclonal Antibody | anti-H1-4 antibody
Histones (HRP)
Gene Names
H1-4; H1E; H1.4; H1F4; RMNS; H1s-4; HIST1H1E; dJ221C16.5
Reactivity
Bovine, Hamster, Human
Applications
ELISA, Western Blot
Purity
Purified by Protein G Affinity Chromatography
Synonyms
Histones; Monoclonal Antibody; Histones (HRP); anti-H1-4 antibody
Host
Mouse
Reactivity
Bovine, Hamster, Human
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2Q2205
Specificity
Recognizes human Histones, H1 and core proteins H2a, H2b, H3, H4. Species Crossreactivity: bovine and hamster
Purity/Purification
Purified by Protein G Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Sequence Length
785
Applicable Applications for anti-H1-4 antibody
ELISA (EIA), Western Blot (WB)
Immunogen
Histones purified from calf thymus. MW: 15-33kD.
Conjugate
HRP
Preparation and Storage
Store at -20 degree C.
Testing Data
(Jurkat cell lysate was probed with MBS602894 at 0.5ug/ml. Proteins were visualized using an IgG (HRP) goat anti-mouse and a chemiluminescence detection system. Arrow indicates Histone H1 + core proteins (~14-33kD).)
Testing Data
(Jurkat cell lysate was probed with MBS602894 at 0.5ug/ml. Proteins were visualized using an IgG (HRP) goat anti-mouse and a chemiluminescence detection system. Arrow indicates Histone H1 + core proteins (~14-33kD).)
Product Categories/Family for anti-H1-4 antibody
References
1. Federation Proceedings (1984). 43:2063. 2. Mizoguchi, E., et al., Antineutrophil Cytoplamic Antibodies in T-Cell Receptor •-Deficient Mice with Chronic Colitis. Gastroenterology (1997) 113:1828-1835. 3. Feng, H., et al., CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans. Nature Cell Biology (1999) 1:486- 492. 4. Brimmell, M., et al., High level expression of differentially localized BAG-1 isoforms in some oestrogen receptor-positive human breast cancers. British Journal of Cancer (1999) 81:1042-1051.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
1433
NCBI Official Full Name
Homo sapiens H1.4 linker histone, cluster member (H1-4), mRNA
NCBI Official Synonym Full Names
H1.4 linker histone, cluster member
NCBI Official Symbol
H1-4
NCBI Official Synonym Symbols
H1E; H1.4; H1F4; RMNS; H1s-4; HIST1H1E; dJ221C16.5
NCBI Protein Information
histone H1.4
UniProt Protein Name
Histone H1.4
UniProt Gene Name
HIST1H1E
UniProt Synonym Gene Names
H1F4
UniProt Entry Name
H14_HUMAN
NCBI Description
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
Research Articles on H1-4
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Product Notes
The H1-4 hist1h1e (Catalog #AAA6244158) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Histones (HRP) reacts with Bovine, Hamster, Human and may cross-react with other species as described in the data sheet. AAA Biotech's Histones can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the H1-4 hist1h1e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Histones, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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