Basigin Recombinant Protein | Bsg recombinant protein

Recombinant Mouse Basigin Protein

Cat. Num. AAA2556781

• Gene Names: Bsg; HT-7; CD147; EMMPRIN; AI115436; AI325119
• Purity: >90% as determined by reducing SDS-PAGE.
• Synonyms: Basigin; Recombinant Mouse Basigin Protein; Basic immunoglobulin superfamily; HT7 antigen; Membrane glycoprotein gp42; CD147; Bsg; Bsg recombinant protein

• Host: Human Cells
• Purity/Purification: >90% as determined by reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 mum filtered solution of PBS, pH 7.4.
• Sequence Length: 273

• Species: Mouse
• Endotoxin: <1.0 EU per mug as determined by LAL test.
• Fragment: Met 1-Arg 209
• Fusion Tag: C-6His
• Preparation and Storage: Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.; Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days.; Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.

SDS-Page

Related Product Information for Bsg recombinant protein

Protein Construction: Recombinant Mouse Basigin is produced by our Mammalian expression system and the target gene encoding Ala22-Arg325 is expressed with a 6His tag at the C-terminus.

Background: Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression.

NCBI and Uniprot Product Information

• NCBI GI #: 116014342
• NCBI GeneID: 12215
• NCBI Accession #: NP_001070652.1
• NCBI GenBank Nucleotide #: NM_001077184.1
• UniProt Accession #: P18572; Q6LDB0; Q7TSC0
• Molecular Weight: Molecular Mass: 34.1kDa; Actual Protein Molecular Mass: 45-60kDa
• NCBI Official Full Name: basigin isoform 2
• NCBI Official Synonym Full Names: basigin
• NCBI Official Symbol: Bsg
• NCBI Official Synonym Symbols: HT-7; CD147; EMMPRIN; AI115436; AI325119
• NCBI Protein Information: basigin
• UniProt Protein Name: Basigin
• Protein Family: Basigin
• UniProt Gene Name: Bsg

Uniprot Description

Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3, SLC16A8, SLC16A11 and SLC16A12 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.