MYBBP1A blocking peptide

MYBBP1A Antibody(N-term) Blocking peptide

• Gene Names: MYBBP1A; P160; PAP2
• Synonyms: MYBBP1A; MYBBP1A Antibody(N-term) Blocking peptide; Myb-binding protein 1A; P160; MYBBP1A blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 1328

• Cellular Location: Cytoplasm. Nucleus. Nucleus, nucleolus. Note: Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity) Predominantly nucleolar.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for MYBBP1A blocking peptide

May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter.

NCBI and Uniprot Product Information

• NCBI GI #: 71153825
• NCBI GeneID: 10514
• UniProt Accession #: Q9BQG0; Q86VM3; Q9BW49; Q9P0V5; Q9UF99
• Molecular Weight: 149,367 Da
• NCBI Official Full Name: Myb-binding protein 1A
• NCBI Official Synonym Full Names: MYB binding protein 1a
• NCBI Official Symbol: MYBBP1A
• NCBI Official Synonym Symbols: P160; PAP2
• NCBI Protein Information: myb-binding protein 1A
• UniProt Protein Name: Myb-binding protein 1A
• Protein Family: Myb-binding protein
• UniProt Gene Name: MYBBP1A
• UniProt Synonym Gene Names: P160
• UniProt Entry Name: MBB1A_HUMAN

NCBI Description

This gene encodes a nucleolar transcriptional regulator that was first identified by its ability to bind specifically to the Myb proto-oncogene protein. The encoded protein is thought to play a role in many cellular processes including response to nucleolar stress, tumor suppression and synthesis of ribosomal DNA. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Uniprot Description

May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter.