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Western Blot (WB) (All lanes : Anti-MYBBP1A Antibody at 1:5000 dilutionLane 1: Hela whole cell lysateLane 2: Jurkat whole cell lysateLane 3: A431 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 149 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Mouse anti-Human MYBBP1A Monoclonal Antibody | anti-MYBBP1A antibody

MYBBP1A Antibody

Gene Names
MYBBP1A; P160; PAP2
Reactivity
Human
Applications
Western Blot, ELISA
Synonyms
MYBBP1A; Monoclonal Antibody; MYBBP1A Antibody; Myb-binding protein 1A; P160; anti-MYBBP1A antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Specificity
This MYBBP1A antibody is generated from a mouse immunized with a recombinant protein between 1104-1328 amino acids from human MYBBP1A.
Form/Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Sequence Length
1332
Applicable Applications for anti-MYBBP1A antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB:~~1:5000
Subtitle
Purified Mouse Monoclonal Antibody (Mab)
Cellular Location
Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity) Predominantly nucleolar. {ECO:0000250|UniProtKB:Q7TPV4}.
Antigen Type
Recombinant Protein
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-MYBBP1A Antibody at 1:5000 dilutionLane 1: Hela whole cell lysateLane 2: Jurkat whole cell lysateLane 3: A431 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 149 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (All lanes : Anti-MYBBP1A Antibody at 1:5000 dilutionLane 1: Hela whole cell lysateLane 2: Jurkat whole cell lysateLane 3: A431 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 149 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-MYBBP1A antibody
May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter.
Product Categories/Family for anti-MYBBP1A antibody
References
Keough R.,et al.Genomics 62:483-489 (1999). Wiemann S.,et al.Genome Res. 11:422-435 (2001). Bechtel S.,et al.BMC Genomics 8:399-399 (2007). Scherl A.,et al.Mol. Biol. Cell 13:4100-4109 (2002). Olsen J.V.,et al.Cell 127:635-648 (2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
148855 Da
NCBI Official Full Name
myb-binding protein 1A isoform 1
NCBI Official Synonym Full Names
MYB binding protein 1a
NCBI Official Symbol
MYBBP1A
NCBI Official Synonym Symbols
P160; PAP2
NCBI Protein Information
myb-binding protein 1A
UniProt Protein Name
Myb-binding protein 1A
Protein Family
UniProt Gene Name
MYBBP1A
UniProt Synonym Gene Names
P160
UniProt Entry Name
MBB1A_HUMAN

NCBI Description

This gene encodes a nucleolar transcriptional regulator that was first identified by its ability to bind specifically to the Myb proto-oncogene protein. The encoded protein is thought to play a role in many cellular processes including response to nucleolar stress, tumor suppression and synthesis of ribosomal DNA. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Uniprot Description

May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter.

Research Articles on MYBBP1A

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Product Notes

The MYBBP1A mybbp1a (Catalog #AAA9217057) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MYBBP1A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MYBBP1A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB:~~1:5000. Researchers should empirically determine the suitability of the MYBBP1A mybbp1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYBBP1A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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