HSP10 blocking peptide

HSP10 (K80) Peptide

Cat. Num. AAA3000605

• Applications: Blocking
• Purity: Synthetic peptide HSP10 (K80). (Note: the amino acid sequence is proprietary).; The purity is >98%.
• Synonyms: HSP10; HSP10 (K80) Peptide; Hsp10; 10 kDa chaperonin; Chaperonin 10; CPN10; Early-pregnancy factor; EPF; HSPE1; HSP10 blocking peptide

• Specificity: This peptide can be used with studies using MBS3000604 HSP10 (K80) pAb.
• Purity/Purification: Synthetic peptide HSP10 (K80). (Note: the amino acid sequence is proprietary).; The purity is >98%.
• Form/Format: 1 mg/ml in DI water.
• Sequence Length: 102

• Applicable Applications for HSP10 blocking peptide: Blocking
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Related Product Information for HSP10 blocking peptide

The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the low molecular weight HSPs, the immunophilins and the HSP 110 family. The low molecular weight family includes HSP 10, HSP 20, HSP 27 (Heme Oxygenase 1), HSP 32 and HSP 40. Chaperonins are ubiquitous, indispensable proteins that facilitate protein folding in an ATP-dependent manner, enhancing the yield of properly folded substrate protein under conditions where spontaneous folding does not occur. Chaperonins are typified by the E. coli heat-shock proteins GroEL and GroES (HSP 10). HSP 10 is a heptameric ring of identical 10 kDa subunits that binds to each end of GroEL to form a symmetric, functional heterodimer.

NCBI and Uniprot Product Information

• NCBI GI #: 4504523
• NCBI Accession #: NP_002148.1
• NCBI GenBank Nucleotide #: NP_002148.1
• UniProt Accession #: P61604
• NCBI Official Full Name: 10 kDa heat shock protein, mitochondrial
• UniProt Protein Name: 10 kDa heat shock protein, mitochondrial
• Protein Family: 10 kDa heat shock protein
• UniProt Gene Name: HSPE1
• UniProt Synonym Gene Names: Hsp10; CPN10; EPF
• UniProt Entry Name: CH10_HUMAN

Uniprot Description

HSPE1: Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. Belongs to the GroES chaperonin family.

Protein type: Mitochondrial

Chromosomal Location of Human Ortholog: 2q33.1

Cellular Component: membrane; mitochondrion; mitochondrial matrix

Molecular Function: protein binding; chaperone binding; unfolded protein binding; ATP binding

Biological Process: caspase activation; osteoblast differentiation; protein folding; response to unfolded protein