Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

EHHADH blocking peptide

EHHADH Antibody (C-term) Blocking Peptide

Gene Names
EHHADH; LBP; ECHD; LBFP; PBFE; FRTS3; L-PBE
Synonyms
EHHADH; EHHADH Antibody (C-term) Blocking Peptide; Peroxisomal bifunctional enzyme; PBE; PBFE; Enoyl-CoA hydratase/3;2-trans-enoyl-CoA isomerase; 3-hydroxyacyl-CoA dehydrogenase; ECHD; EHHADH blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human EHHADH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
723
Cellular Location
Peroxisome.
Tissue Location
Liver and kidney. Strongly expressed in the terminal segments of the proximal tubule. Lower amounts seen in the brain.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
69,154 Da
NCBI Official Full Name
Peroxisomal bifunctional enzyme
NCBI Official Synonym Full Names
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
NCBI Official Symbol
EHHADH
NCBI Official Synonym Symbols
LBP; ECHD; LBFP; PBFE; FRTS3; L-PBE
NCBI Protein Information
peroxisomal bifunctional enzyme
UniProt Protein Name
Peroxisomal bifunctional enzyme
UniProt Gene Name
EHHADH
UniProt Synonym Gene Names
ECHD; PBE; PBFE
UniProt Entry Name
ECHP_HUMAN

NCBI Description

The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Uniprot Description

EHHADH: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - butanoate; EC 5.3.3.8; EC 1.1.1.35; EC 4.2.1.17; Carbohydrate Metabolism - propanoate; Mitochondrial; Isomerase; Amino Acid Metabolism - tryptophan; Lipid Metabolism - fatty acid; Amino Acid Metabolism - lysine degradation; Secondary Metabolites Metabolism - limonene and pinene degradation; Oxidoreductase; Other Amino Acids Metabolism - beta-alanine; Lyase; Amino Acid Metabolism - valine, leucine and isoleucine degradation

Chromosomal Location of Human Ortholog: 3q26.3-q28

Cellular Component: peroxisomal matrix; peroxisome

Molecular Function: 3-hydroxyacyl-CoA dehydrogenase activity; enzyme binding; long-chain-enoyl-CoA hydratase activity; protein binding; receptor binding

Biological Process: cellular lipid metabolic process; internal protein amino acid acetylation

Disease: Fanconi Renotubular Syndrome 3

Research Articles on EHHADH

Similar Products

Product Notes

The EHHADH ehhadh (Catalog #AAA9227756) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "EHHADH, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.