Rabbit anti-Human EHHADH Polyclonal Antibody | anti-EHHADH antibody

Anti-EHHADH Antibody

Cat. Num. AAA415490

• Gene Names: EHHADH; LBP; ECHD; LBFP; PBFE; FRTS3; L-PBE
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity purified
• Synonyms: EHHADH; Polyclonal Antibody; Anti-EHHADH Antibody; anti-EHHADH antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purified
• Form/Format: Liquid
• Concentration: 100ug/100ul (varies by lot)
• Sequence Length: 484

• Applicable Applications for anti-EHHADH antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Optimal dilutions to be determined by researchers
• Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide
• Immunogen: Recombinant protein
• Preparation and Storage: This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Testing Data

Related Product Information for anti-EHHADH antibody

This gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

NCBI and Uniprot Product Information

• NCBI GI #: 118600889
• NCBI GeneID: 1962
• Molecular Weight: 69,154 Da
• NCBI Official Full Name: EHHADH protein, partial
• NCBI Official Synonym Full Names: enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
• NCBI Official Symbol: EHHADH
• NCBI Official Synonym Symbols: LBP; ECHD; LBFP; PBFE; FRTS3; L-PBE
• NCBI Protein Information: peroxisomal bifunctional enzyme; 3,2-trans-enoyl-CoA isomerase; L-3-hydroxyacyl-CoA dehydrogenase; L-bifunctional protein, peroxisomal; PBE; enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase; peroxisomal enoyl-CoA hydratase
• UniProt Protein Name: Peroxisomal bifunctional enzyme
• Protein Family: Peroxisomal bifunctional enzyme
• UniProt Gene Name: EHHADH
• UniProt Entry Name: ECHP_HUMAN

NCBI Description

The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Uniprot Description

EHHADH: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lyase; EC 5.3.3.8; Carbohydrate Metabolism - butanoate; Carbohydrate Metabolism - propanoate; Lipid Metabolism - fatty acid; Secondary Metabolites Metabolism - limonene and pinene degradation; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Oxidoreductase; EC 1.1.1.35; Amino Acid Metabolism - lysine degradation; EC 4.2.1.17; Other Amino Acids Metabolism - beta-alanine; Mitochondrial; Isomerase; Amino Acid Metabolism - tryptophan

Chromosomal Location of Human Ortholog: 3q26.3-q28

Cellular Component: mitochondrion; peroxisome; cytosol

Molecular Function: enzyme binding; enoyl-CoA hydratase activity; dodecenoyl-CoA delta-isomerase activity; coenzyme binding; 3-hydroxyacyl-CoA dehydrogenase activity; receptor binding

Biological Process: fatty acid beta-oxidation; internal protein amino acid acetylation

Disease: Fanconi Renotubular Syndrome 3