Structure
STAT5 inhibitor 17f Biochemical
STAT5 inhibitor 17f
Purity
>98% (HPLC)
Synonyms
STAT5 inhibitor 17f; STAT5-IN-17f; STAT5 inhibitor 17f biochemical
Purity/Purification
>98% (HPLC)
Target
STAT
Receptor
STAT
Chemical Name
1-(2-((1H-Indol-5-yl)oxy)ethyl)-4, 4-dimethyl-6-(pyridin-3-yl)-1, 2, 3, 4-tetrahydroquinoline
SMILES
CC1(C)CCN(CCOC2=CC3=C(NC=C3)C=C2)C4=C1C=C(C5=CC=CN=C5)C=C4
Molecular Formula
C26H27N3O
CAS Number
2111834-61-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for STAT5 inhibitor 17f biochemical
A novel potent, selective inhibitor of phosphorylation and transcriptional activity of STAT5, but not STAT3, AKT, or Erk1/2 phosphorylation; inhibits the growth of acute and chronic myeloid leukemia cells and the phosphorylation and transcriptional activity of STAT5; inhibits KU812 and K562 cell growth with IC50 of 9 and 5uM, respectively, demonstrates highly potent antileukemic effect with minimal effects on bone marrow stromal cells.
Product Categories/Family for STAT5 inhibitor 17f biochemical
References
1. Juen L, et al. J Med Chem. 2017 Jul 27; 60 (14):6119-6136.
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Product Notes
The STAT5 inhibitor 17f (Catalog #AAA3603355) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "STAT5 inhibitor 17f, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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