Structure
SCH 412348 Biochemical
SCH 412348
Purity
>98% (HPLC)
Synonyms
SCH 412348; SCH412348; SCH 412348 biochemical
Purity/Purification
>98% (HPLC)
Target
Adenosine Receptor
Receptor
Adenosine Receptor
Chemical Name
7-[2-[4-(2, 4-Difluorophenyl)-1-piperazinyl]ethyl]-2-(2-furanyl)-7H-pyrazolo[4, 3-e][1, 2, 4]triazolo[1, 5-c]pyrimidin-5-amine
SMILES
NC1=NC(N(CCN2CCN(C3=CC=C(F)C=C3F)CC2)N=C4)=C4C5=NC(C6=CC=CO6)=NN15
Molecular Formula
C22H21F2N9O
CAS Number
377727-26-9
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for SCH 412348 biochemical
SCH 412348 is a potent and highly selective A2A receptor competitive antagonist with Ki of 0.6nM; has >1000-fold selectivity over all other adenosine receptors; attenuates hypolocomotion induced by the A2AR agonist CGS-21680; exhibits antidepressant-like profiles in models of behavioral despair. Parkinson Disease Phase 2 Discontinued
Product Categories/Family for SCH 412348 biochemical
References
1. Neustadt BR, et al. Bioorg Med Chem Lett. 2009 Feb 1; 19 (3):967-71.
2. Smith KM, et al. Eur J Pharmacol. 2014 Apr 5; 728:31-8.
3. Grauer SM, et al. Psychopharmacology (Berl). 2014 Apr; 231 (7):1325-37.
2. Smith KM, et al. Eur J Pharmacol. 2014 Apr 5; 728:31-8.
3. Grauer SM, et al. Psychopharmacology (Berl). 2014 Apr; 231 (7):1325-37.
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Product Notes
The SCH 412348 (Catalog #AAA3604302) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SCH 412348, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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