Structure
CDN1163 Biochemical
CDN1163
Purity
>98% (HPLC)
Synonyms
CDN1163; CDN 1163; CDN-1163; CDN1163 biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 50mg/mL (156.06mM)
H2O: <0.1mg/mL
H2O: <0.1mg/mL
Target
Calcium Channel
Receptor
Calcium Channel
Chemical Name
4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide
SMILES
O=C(NC1=C2N=C(C)C=CC2=CC=C1)C3=CC=C(OC(C)C)C=C3
Molecular Formula
C20H20N2O2
CAS Number
892711-75-0
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for CDN1163 biochemical
CDN1163 (CDN-1163) is a small molecule, allosteric activator of SERCA2, dose-dependently increases the Vmax of SERCA2 Ca2+-ATPase activity in ER microsomes; increases Ca2+-ATPase activity and significantly enhances Ca2+ uptake into the ER, attenuates H2O2-stimulated cell death in HEK cells; improves glucose homeostasis and metabolic parameters, increases glucose tolerance in ob/ob mice; CDN1163 reduces lipid accumulation and decreases lipogenesis in obese mice livers.
Product Categories/Family for CDN1163 biochemical
References
1. Krajnak K, et al. Bioorg Med Chem Lett. 2018 May 15; 28 (9):1591-1594.
2. Kang S, et al. J Biol Chem. 2016 Mar 4; 291 (10):5185-98.
3. Dahl R. Bioorg Med Chem. 2017 Jan 1; 25 (1):53-57.
4. Cornea RL, et al. J Biomol Screen. 2013 Jan; 18 (1):97-107.
2. Kang S, et al. J Biol Chem. 2016 Mar 4; 291 (10):5185-98.
3. Dahl R. Bioorg Med Chem. 2017 Jan 1; 25 (1):53-57.
4. Cornea RL, et al. J Biomol Screen. 2013 Jan; 18 (1):97-107.
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Product Notes
The CDN1163 (Catalog #AAA3606433) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CDN1163, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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