Structure
Setmelanotide Biochemical
Setmelanotide
Purity
98.85% (LCMS)
Synonyms
Setmelanotide; RM-493; BIM-22493; IRC-022493; Setmelanotide biochemical
Purity/Purification
98.85% (LCMS)
Suitability
DMSO
Target
Melanocortin Receptor
Receptor
Melanocortin Receptor
Chemical Name
L-Cysteinamide, N2-acetyl-L-arginyl-L-cysteinyl-D-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-, cyclic(2-->8)-disulfide
SMILES
CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)N1)NC(=O)C(CCCN=C(N)N)NC(=O)C)C(=O)N)CC2=CNC3=CC=CC=C32)CCCN=C(N)N)CC4=CC=CC=C4)CC5=CN=CN5
Molecular Formula
C49H68N18O9S2
CAS Number
920014-72-8
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Setmelanotide biochemical
Setmelanotide (RM-493, BIM-22493, IRC-022493) is a peptide, non-selective melanocortin receptor agonist with binding Ki of 3.9/10/2.1 for hMC1R/hMC3R/hMC4R, respectively; exhibits weak activity at MC5R (EC50>1uM) and inactive at the mouse MC2R (EC50>10uM); acutely improves glucose homeostasis, causes weight loss and improves hyperinsulinemia and fatty liver in diet induced obese mice. Obesity Phase 3 Clinical
Product Categories/Family for Setmelanotide biochemical
References
1. Kumar KG, et al. Peptides. 2009 Oct; 30 (10):1892-900.
2. Chen KY, et al. J Clin Endocrinol Metab. 2015 Apr; 100 (4):1639-45.
3. Bischof JM, et al. Br J Pharmacol. 2016 Sep; 173 (17):2614-21.
2. Chen KY, et al. J Clin Endocrinol Metab. 2015 Apr; 100 (4):1639-45.
3. Bischof JM, et al. Br J Pharmacol. 2016 Sep; 173 (17):2614-21.
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Product Notes
The Setmelanotide (Catalog #AAA3606595) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Setmelanotide, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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