Human HLA-B associated transcript 3 ELISA Kit | BAT3 elisa kit

Human HLA-B associated transcript 3, BAT3 ELISA Kit

Cat. Num. AAA925398

• Reactivity: Human
• Synonyms: HLA-B associated transcript 3; Human HLA-B associated transcript 3; BAT3 ELISA Kit; Human HLA-B associated transcript 3 (BAT3) ELISA kit; DAQB-195H10.3; BAG-6; BAG6; D6S52E; G3; HLA-B associated transcript-3; large proline-rich protein BAT3; scythe HLA-B associated transcript 3 (BAT3) ; BAT3 elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of Human BAT3. No significant cross-reactivity or interference between Human BAT3 and analogues was observed.
• Sequence Length: 1126

• Samples: Serum, plasma and tissue homogenates
• Assay Type: Sandwich
• Detection Range: 62.5 pg/ml-4000 pg/ml
• Sensitivity: 15.6 pg/ml
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%; Three samples of known concentration were tested twenty times on one plate to assess.; Inter-assay Precision (Precision between assays): CV% is less than 10%; Three samples of known concentration were tested in twenty assays to assess.
• Detection Wavelength: 450nm
• Sample Volume: 50-100ul
• Protein Biological Process 1: Apoptosis/Autophagy
• Protein Biological Process 3: Apoptosis
• Preparation and Storage: Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for BAT3 elisa kit

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for BAT3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any BAT3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for BAT3 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of BAT3 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 15277262
• UniProt Accession #: P0C9F0
• Molecular Weight: 14,969 Da
• NCBI Official Full Name: BAT3
• UniProt Protein Name: Protein MGF 100-1R
• Protein Family: Burkholderia TALE-like protein
• UniProt Entry Name: 1001R_ASFK5

NCBI Description

This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Function: Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages