Anterior Gradient Protein 3 Homolog/AG-3/BCMP11/AGR3 Recombinant Protein | AG-3/BCMP11/AGR3 recombinant protein
Recombinant Human Anterior Gradient Protein 3 Homolog/AG-3/BCMP11/AGR3 Protein (C-6His)
Gene Names
AGR3; AG3; AG-3; HAG3; hAG-3; BCMP11; PDIA18
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Anterior Gradient Protein 3 Homolog/AG-3/BCMP11/AGR3; Recombinant Human Anterior Gradient Protein 3 Homolog/AG-3/BCMP11/AGR3 Protein (C-6His); Anterior Gradient Protein 3 Homolog; AG-3; AG3; hAG-3; Breast Cancer Membrane Protein 11; AGR3; BCMP11; AG-3/BCMP11/AGR3 recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mM Tris HCl, 150mM NaCl, 2mM EDTA, pH 8.5.
Sequence Positions
Ile22-Leu166
Sequence Length
166
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
C-6His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for AG-3/BCMP11/AGR3 recombinant protein
Anterior Gradient Protein 2(AG-2) and Anterior Gradient Protein 3 (AG-3) are human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan (hAG-3 protein). AG-3 could serve as a prognostic marker for survival in patients with low grade and high grade serous ovarian carcinomas.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 18.0 kDa
Actual Protein Molecular Mass: 16 kDa
Actual Protein Molecular Mass: 16 kDa
NCBI Official Full Name
anterior gradient protein 3
NCBI Official Synonym Full Names
anterior gradient 3, protein disulphide isomerase family member
NCBI Official Symbol
AGR3
NCBI Official Synonym Symbols
AG3; AG-3; HAG3; hAG-3; BCMP11; PDIA18
NCBI Protein Information
anterior gradient protein 3
UniProt Protein Name
Anterior gradient protein 3
UniProt Gene Name
AGR3
UniProt Synonym Gene Names
BCMP11; PDIA18; AG-3; AG3; hAG-3
NCBI Description
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016]
Uniprot Description
Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells.
Research Articles on AG-3/BCMP11/AGR3
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Product Notes
The AG-3/BCMP11/AGR3 agr3 (Catalog #AAA2552360) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Ile22-Leu166. It is sometimes possible for the material contained within the vial of "Anterior Gradient Protein 3 Homolog/AG-3/BCMP11/AGR3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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