Immunohistochemistry (IHC)-Paraffin
(Immunohistochemistry staining of AGR3 with mouse monoclonal AGR3.1 in paraffin-embedded sections of breast carcinoma.)
Mouse anti-Human AGR3 Antibody | anti-AGR3 antibody
Anti-AGR3 Purified
Gene Names
AGR3; AG3; AG-3; HAG3; hAG-3; BCMP11; PDIA18
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
AGR3; Anti-AGR3 Purified; anterior gradient 3; protein disulphide isomerase; AG3; HAG3; anti-AGR3 antibody
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
AGR3.1
Specificity
The antibody AGR3.1 recognizes the epitope HETTDKNLS within the AGR3 (AG3) protein (19-20 kDa); a secreted cytoplasmic protein which can serve as a marker of carcinogenesis.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
166
Applicable Applications for anti-AGR3 antibody
Western Blot (WB), Immunohistochemistry (IHC) Frozen/Paraffin, Immunocytochemistry (ICC)
Immunogen
Purified human AGR3 protein
Preparation and Storage
Store at 2-8 degree C.
Immunohistochemistry (IHC)-Paraffin
(Immunohistochemistry staining of AGR3 with mouse monoclonal AGR3.1 in paraffin-embedded sections of breast carcinoma.)
Immunohistochemistry (IHC)-Paraffin
(Immunohistochemistry staining of AGR3 with mouse monoclonal AGR3.1 in paraffin-embedded sections of breast carcinoma.)
Related Product Information for anti-AGR3 antibody
AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
anterior gradient protein 3
NCBI Official Synonym Full Names
anterior gradient 3, protein disulphide isomerase family member
NCBI Official Symbol
AGR3
NCBI Official Synonym Symbols
AG3; AG-3; HAG3; hAG-3; BCMP11; PDIA18
NCBI Protein Information
anterior gradient protein 3
UniProt Protein Name
Anterior gradient protein 3 homolog
Protein Family
UniProt Gene Name
AGR3
UniProt Synonym Gene Names
BCMP11; AG-3; AG3; hAG-3
UniProt Entry Name
AGR3_HUMAN
NCBI Description
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016]
Uniprot Description
AGR3: Belongs to the AGR family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 7p21.1
Cellular Component: extracellular region
Molecular Function: protein binding
Research Articles on AGR3
Similar Products
Product Notes
The AGR3 agr3 (Catalog #AAA1800335) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-AGR3 Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AGR3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Frozen/Paraffin, Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the AGR3 agr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AGR3, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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