Rabbit anti-Human, Mouse HNRNPH2 Polyclonal Antibody | anti-HNRNPH2 antibody

HNRNPH2 Polyclonal Conjugated Antibody

Cat. Num. AAA9439749

• Gene Names: HNRNPH2; FTP3; HNRPH'; HNRPH2; hnRNPH'
• Reactivity: Human, Mouse
• Applications: Most Applications
• Purity: Affinity purification
• Synonyms: HNRNPH2; Polyclonal Antibody; HNRNPH2 Polyclonal Conjugated Antibody; HNRNPH2 Conjugated Antibody; FTP3; HNRPH'; HNRPH2; MRXSB; hnRNPH'; NRPH2; heterogeneous nuclear ribonucleoprotein H2; anti-HNRNPH2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Form/Format: 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

• Applicable Applications for anti-HNRNPH2 antibody: Most Applications
• Application Notes: Suggested Dilution:; AF350 conjugated: most applications: 1:50-1:250; AF405 conjugated: most applications: 1:50-1:250; AF488 conjugated: most applications: 1:50-1:250; AF555 conjugated: most applications: 1:50-1:250; AF594 conjugated: most applications: 1:50-1:250; AF647 conjugated: most applications: 1:50-1:250; AF680 conjugated: most applications: 1:50-1:250; AF750 conjugated: most applications: 1:50-1:250; Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
• Immunogen: Recombinant fusion protein of human HNRNPH2 (NP_062543.1).
• Conjugation: Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation Emission: AF350: 346nm/442nm
• Preparation and Storage: Store at 4 degree C for 6 months.

Related Product Information for anti-HNRNPH2 antibody

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed.

NCBI and Uniprot Product Information

• NCBI GI #: 9624998
• NCBI GeneID: 3188
• NCBI Accession #: NP_062543.1
• NCBI GenBank Nucleotide #: NM_019597.4
• UniProt Accession #: P55795; Q9HHA7; A1L400
• Molecular Weight: 49,264 Da
• NCBI Official Full Name: heterogeneous nuclear ribonucleoprotein H2
• NCBI Official Synonym Full Names: heterogeneous nuclear ribonucleoprotein H2 (H')
• NCBI Official Symbol: HNRNPH2
• NCBI Official Synonym Symbols: FTP3; HNRPH'; HNRPH2; hnRNPH'
• NCBI Protein Information: heterogeneous nuclear ribonucleoprotein H2; FTP-3; hnRNP H'; hnRNP H2; heterogeneous nuclear ribonucleoprotein H-prime
• UniProt Protein Name: Heterogeneous nuclear ribonucleoprotein H2
• Protein Family: Heterogeneous nuclear ribonucleoprotein
• UniProt Gene Name: HNRNPH2
• UniProt Synonym Gene Names: FTP3; HNRPH2; hnRNP H2; hnRNP H'
• UniProt Entry Name: HNRH2_HUMAN

NCBI Description

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed. [provided by RefSeq, Jan 2011]

Uniprot Description

hnRNP H2: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG).

Protein type: RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: Xq22

Cellular Component: nucleoplasm; membrane; nucleus; ribonucleoprotein complex

Molecular Function: RNA binding; nucleotide binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression