Retinol dehydrogenase 11 Recombinant Protein | RDH11 recombinant protein
Recombinant Human Retinol dehydrogenase 11
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity. [provided by RefSeq, Nov 2011]
Uniprot Description
RDH11: Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.300; Membrane protein, integral; Oxidoreductase
Chromosomal Location of Human Ortholog: 14q24.1
Cellular Component: endoplasmic reticulum membrane; intracellular
Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; retinol dehydrogenase activity
Biological Process: retinal metabolic process; retinoid metabolic process; retinol metabolic process
Disease: Retinal Dystrophy, Juvenile Cataracts, And Short Stature Syndrome
Research Articles on RDH11
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Product Notes
The RDH11 rdh11 (Catalog #AAA9420605) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Cytoplasmic Domain, 22-318aa. The Recombinant Human Retinol dehydrogenase 11 reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Retinol dehydrogenase 11, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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