SDS-PAGE
Retinol dehydrogenase 11 Recombinant Protein | RDH11 recombinant protein
Recombinant Human Retinol dehydrogenase 11
SDS-PAGE
SDS-PAGE
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity. [provided by RefSeq, Nov 2011]
Uniprot Description
RDH11: Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.1.1.300; Membrane protein, integral; Cofactor and Vitamin Metabolism - retinol; Oxidoreductase
Chromosomal Location of Human Ortholog: 14q24.1
Cellular Component: endoplasmic reticulum membrane; integral to membrane; intracellular; photoreceptor inner segment
Molecular Function: retinol dehydrogenase activity
Biological Process: adaptation of rhodopsin mediated signaling; fat-soluble vitamin metabolic process; phototransduction, visible light; retinal metabolic process; retinoid metabolic process; retinol metabolic process; vitamin metabolic process
Disease: Retinal Dystrophy, Juvenile Cataracts, And Short Stature Syndrome
Research Articles on RDH11
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Product Notes
The RDH11 rdh11 (Catalog #AAA969601) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 22-318aa; Cytoplasmic Domain. The amino acid sequence is listed below: PQIRKMLSSG VCTSTVQLPG KVVVVTGANT GIGKETAKEL AQRGARVYLA CRDVEKGELV AKEIQTTTGN QQVLVRKLDL SDTKSIRAFA KGFLAEEKHL HVLINNAGVM MCPYSKTADG FEMHIGVNHL GHFLLTHLLL EKLKESAPSR IVNVSSLAHH LGRIHFHNLQ GEKFYNAGLA YCHSKLANIL FTQELARRLK GSGVTTYSVH PGTVQSELVR HSSFMRWMWW LFSFFIKTPQ QGAQTSLHCA LTEGLEILSG NHFSDCHVAW VSAQARNETI ARRLWDVSCD LLGLPID. It is sometimes possible for the material contained within the vial of "Retinol dehydrogenase 11, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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