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SDS-Page (Gel: 8%SDS-PAGE Lysate: 40 ug, Lane: Mouse Pancreas tissue lysate, Primary antibody:CDK14 antibody at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)

Rabbit anti-Human, Mouse CDK14 Polyclonal Antibody | anti-CDK14 antibody

CDK14 Antibody

Gene Names
CDK14; PFTK1; PFTAIRE1
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Antigen affinity purification
Synonyms
CDK14; Polyclonal Antibody; CDK14 Antibody; PFTK1; PFTAIRE1; anti-CDK14 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total CDK14 protein.
Purity/Purification
Antigen affinity purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.2mg/ml (varies by lot)
Sequence Length
469
Applicable Applications for anti-CDK14 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:200-1000
Immunogen
Synthetic peptide of human CDK14
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

SDS-Page

(Gel: 8%SDS-PAGE Lysate: 40 ug, Lane: Mouse Pancreas tissue lysate, Primary antibody:CDK14 antibody at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)

SDS-Page (Gel: 8%SDS-PAGE Lysate: 40 ug, Lane: Mouse Pancreas tissue lysate, Primary antibody:CDK14 antibody at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)
Related Product Information for anti-CDK14 antibody
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.
Product Categories/Family for anti-CDK14 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,760 Da
NCBI Official Full Name
cyclin-dependent kinase 14 isoform a
NCBI Official Synonym Full Names
cyclin dependent kinase 14
NCBI Official Symbol
CDK14
NCBI Official Synonym Symbols
PFTK1; PFTAIRE1
NCBI Protein Information
cyclin-dependent kinase 14
UniProt Protein Name
Cyclin-dependent kinase 14
Protein Family
UniProt Gene Name
CDK14
UniProt Synonym Gene Names
KIAA0834; PFTK1; hPFTAIRE1
UniProt Entry Name
CDK14_HUMAN

NCBI Description

PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 [PubMed 11313143]).[supplied by OMIM, Mar 2008]

Uniprot Description

CDK14: a protein kinase of the CDK family. May play a role in meiosis as well as in neuron differentiation and/or function. Highly expressed in brain, pancreas, kidney, heart, testis and ovary. Two alternatively spliced isoforms have been described.

Protein type: CDK family; CDK/TAIRE subfamily; CMGC group; Cell cycle regulation; EC 2.7.11.22; Kinase, protein; Motility/polarity/chemotaxis; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor); TAIRE subfamily

Chromosomal Location of Human Ortholog: 7q21-q22

Cellular Component: cytoplasm; nucleus; plasma membrane

Molecular Function: cyclin binding; cyclin-dependent protein kinase activity; protein binding

Biological Process: G2/M transition of mitotic cell cycle

Research Articles on CDK14

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Product Notes

The CDK14 cdk14 (Catalog #AAA9417213) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDK14 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CDK14 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:200-1000. Researchers should empirically determine the suitability of the CDK14 cdk14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDK14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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