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Western Blot (WB) (Western blot analysis of MLIP in 293 cell lysate with MLIP antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)

Rabbit anti-Human MLIP Polyclonal Antibody | anti-MLIP antibody

MLIP Antibody

Gene Names
MLIP; C6orf142
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
MLIP; Polyclonal Antibody; MLIP Antibody; Muscle enriched A-type lamin interacting protein; C6orf142; anti-MLIP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
At least three isoforms of MLIP are known to exist.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
458
Applicable Applications for anti-MLIP antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against a 16 amino acid peptide near the carboxy terminus of human MLIP.
Target Name
MLIP
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of MLIP in 293 cell lysate with MLIP antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)

Western Blot (WB) (Western blot analysis of MLIP in 293 cell lysate with MLIP antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-MLIP antibody
The muscle-enriched A-type lamin-interacting protein (MLIP) is ubiquitously expressed, although most predominantly in heart, skeletal and smooth muscle, and interacts directly and co-localizes with lamin A and C in the nuclear envelope. MLIP also co-localizes with promyelocytic leukemia (PML) bodies within the nucleus. Decreasing lamin A/C expression with siRNA results in the upregulation and mislocalization of MLIP, suggesting that MLIP localization to the nuclear envelope is dependent on the lamin proteins. It has been suggested that MLIP may function as a tethering protein linking LMNA to factors within the nuclear envelope of within PML bodies
Product Categories/Family for anti-MLIP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
97,558 Da
NCBI Official Full Name
muscular LMNA-interacting protein isoform 3
NCBI Official Synonym Full Names
muscular LMNA-interacting protein
NCBI Official Symbol
MLIP
NCBI Official Synonym Symbols
C6orf142
NCBI Protein Information
muscular LMNA-interacting protein
UniProt Protein Name
Muscular LMNA-interacting protein
UniProt Gene Name
MLIP
UniProt Synonym Gene Names
C6orf142
UniProt Entry Name
MLIP_HUMAN

Uniprot Description

MLIP: 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 6p12.1

Cellular Component: PML body; nuclear lumen; nuclear envelope

Biological Process: negative regulation of transcription from RNA polymerase II promoter

Research Articles on MLIP

Similar Products

Product Notes

The MLIP mlip (Catalog #AAA9406303) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MLIP Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MLIP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the MLIP mlip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MLIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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