Mouse phosphatidylinositol-3, 4, 5-trisphosphate-dependent Rac exchange factor 2 ELISA Kit | PREX2 elisa kit
Mouse Phosphatidylinositol 3, 4, 5-trisphosphate-dependent Rac exchanger 2 protein, PREX2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PREX2: Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein- coupled receptors and phosphoinositide 3-kinase. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs; Phosphatase, regulatory subunit; GEFs, Rac/Rho
Cellular Component: plasma membrane; intracellular
Molecular Function: Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; Rac guanyl-nucleotide exchange factor activity; GTPase activator activity
Biological Process: G-protein coupled receptor protein signaling pathway; phosphoinositide 3-kinase cascade; adult locomotory behavior; dendrite morphogenesis; regulation of Rho protein signal transduction; positive regulation of GTPase activity
Research Articles on PREX2
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Product Notes
The Mouse PREX2 prex2 (Catalog #AAA9343256) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9343256 ELISA Kit recognizes Mouse PREX2. It is sometimes possible for the material contained within the vial of "phosphatidylinositol-3, 4, 5-trisphosphate-dependent Rac exchange factor 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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