Western Blot (WB)
(FEZF1 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the FEZF1 antibody detected the FEZF1 protein (arrow).)
Rabbit anti-Human, mouse FEZF1 Polyclonal Antibody | anti-FEZF1 antibody
FEZF1 Antibody (N-term)
Western Blot (WB)
(FEZF1 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the FEZF1 antibody detected the FEZF1 protein (arrow).)
Western Blot (WB)
(FEZF1 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the FEZF1 antibody detected the FEZF1 protein (arrow).)
Song, I.S., et al. Cancer Res. 69(7):3131-3139(2009)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a transcriptional repressor that belongs to the zinc finger double domain protein family. The encoded protein is thought to play a role in the embryonic migration of gonadotropin-releasing hormone neurons into the brain. Mutations in this gene are associated with hypogonadotropic hypogonadism-22 with anosmia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Uniprot Description
FEZF1: Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors. Belongs to the krueppel C2H2-type zinc-finger protein family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: C2H2-type zinc finger protein; Transcription factor; Motility/polarity/chemotaxis; Cell development/differentiation
Chromosomal Location of Human Ortholog: 7q31.32
Cellular Component: nucleus
Molecular Function: metal ion binding
Biological Process: axon guidance; negative regulation of cell proliferation; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; olfactory bulb development; forebrain anterior/posterior pattern formation; neuron migration; negative regulation of transcription from RNA polymerase II promoter; positive regulation of neuron differentiation
Disease: Hypogonadotropic Hypogonadism 22 With Or Without Anosmia
Research Articles on FEZF1
Similar Products
Product Notes
The FEZF1 fezf1 (Catalog #AAA9213424) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 67-96. The FEZF1 Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FEZF1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the FEZF1 fezf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FEZF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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