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Rabbit SEC31A Polyclonal Antibody | anti-SEC31A antibody

SEC31A

Gene Names
SEC31A; ABP125; ABP130; HSPC275; HSPC334; SEC31L1
Reactivity
Human
Predicted: Rat, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Purified By Protein A/G Column
Synonyms
SEC31A; Polyclonal Antibody; Purified Rabbit Anti Human SEC31A Polyclonal antibody; ABP125; ABP130; HSPC275; HSPC334; SEC31L1; anti-SEC31A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Protein A/G Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
3713
Applicable Applications for anti-SEC31A antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20000-80000
WB: 1:200-1,000
IHC: 1:100-500
Immunogen
Recombinant fragment corresponding to 1001-1205aa of human SEC31A.
Cellular Localization
Cytoplasm, Cytoplasmic Vesicle, Endoplasmic Reticulum, Membrane
Related Product Information for anti-SEC31A antibody
Homo sapiens SEC31 homolog A (S. cerevisiae), mRNA
References
Lippincott-Schwartz J, Roberts TH and Hirschberg K. Secretory protein trafficking and organelle dynamics in living cells. Annu. Rev. Cell Dev. Biol. 16, 557-589 (2000)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
133KD
NCBI Official Full Name
Homo sapiens SEC31 homolog A (S. cerevisiae), mRNA
NCBI Official Synonym Full Names
SEC31 homolog A, COPII coat complex component
NCBI Official Symbol
SEC31A
NCBI Official Synonym Symbols
ABP125; ABP130; HSPC275; HSPC334; SEC31L1
NCBI Protein Information
protein transport protein Sec31A
Protein Family

NCBI Description

The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Research Articles on SEC31A

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Product Notes

The SEC31A (Catalog #AAA8563305) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SEC31A reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SEC31A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20000-80000 WB: 1:200-1,000 IHC: 1:100-500. Researchers should empirically determine the suitability of the SEC31A for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SEC31A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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