Rabbit TCP1 Antibody | anti-TCP1 antibody

TCP1 Antibody

Cat. Num. AAA8501191

• Gene Names: TCP1; CCT1; CCTa; D6S230E; CCT-alpha; TCP-1-alpha
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity purification
• Synonyms: TCP1; TCP1 Antibody; CCT1; CCTa; D6S230E; CCT-alpha; TCP-1-alpha; anti-TCP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Isotype: IgG
• Purity/Purification: Affinity purification
• Sequence Length: 556

• Applicable Applications for anti-TCP1 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200
• Immunogen: Recombinant protein of human TCP1
• Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Preparation and Storage: Store at-20 degree C or-80 degree C. Avoid freeze/thaw cycles.

Testing Data

(Western blot analysis of extracts of various celllines, using TCP1 antibody.)

Related Product Information for anti-TCP1 antibody

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.

Product Categories/Family for anti-TCP1 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

NCBI and Uniprot Product Information

• NCBI GI #: 57863257
• NCBI GeneID: 6950
• NCBI Accession #: NP_110379.2
• NCBI GenBank Nucleotide #: NM_030752.2
• UniProt Accession #: P17987; Q15556; Q5TCM3; E1P5B2
• Molecular Weight: 60kDa
• NCBI Official Full Name: T-complex protein 1 subunit alpha isoform a
• NCBI Official Synonym Full Names: t-complex 1
• NCBI Official Symbol: TCP1
• NCBI Official Synonym Symbols: CCT1; CCTa; D6S230E; CCT-alpha; TCP-1-alpha
• NCBI Protein Information: T-complex protein 1 subunit alpha
• UniProt Protein Name: T-complex protein 1 subunit alpha
• Protein Family: T-complex protein
• UniProt Gene Name: TCP1
• UniProt Synonym Gene Names: CCT1; CCTA; TCP-1-alpha

NCBI Description

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found. [provided by RefSeq, Jun 2010]

Uniprot Description

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.