Testing Data
ST3GAL1 recombinant protein
ST3Gal1, soluble fragment, Human Recombinant
Gene Names
ST3GAL1; ST3O; SIAT4A; SIATFL; ST3GalA; ST3GalIA; Gal-NAc6S; ST3GalA.1; ST3GalIA,1
Purity
>90% by SDS-PAGE
Synonyms
ST3Gal1; soluble fragment; Human Recombinant; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2; 3-sialyltransferase 1; Gal-NAc6S; Gal-beta-1; 3-GalNAc-alpha-2; 3-sialyltransferase; SIATFL; ST3Gal I; ST3GAL1 recombinant protein
Host
Insect cells
Purity/Purification
>90% by SDS-PAGE
Form/Format
Liquid. Sterile filtered solution in 25mM Tris pH7.5 and 150mM NaCl
Concentration
100ug/ml (varies by lot)
Gene Source
Human
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Testing Data
Testing Data
Related Product Information for ST3GAL1 recombinant protein
ST3Gal1 catalyzes transfer of the sialic acid Neu5Ac from CMP-Neu5Ac (cytidine 5'-monophosphono-N-acetylneuraminic acid) to Galbeta1, 3GalNAc on glycoproteins or glycolipids in an alpha2, 3 linkage. It is a type II transmembrane protein that is normally localized to the golgi, but can be cleaved to yield a soluble product. Sialylation of the core-1 structure (Galbeta1, 3GalNAc-O-Ser/Thr) by ST3Gal1 prevents formation of the core-2 structure (GlcNAcbeta1, 6 (Galbeta1, 3) GalNAc-Ser/Thr). On CD8+ T-cells this prevents induction of either apoptosis or differentiation into memory cells. Overexpression of ST3Gal1 in breast cancer cells correlated with the presence of the core-1 based marker SM3, whereas healthy cells displayed a higher ratio of core-2 based epitopes. Overexpression of ST3Gal1 in colorectal carcinoma was found to be related to poor patient survival. Involved in the pathway protein glycosylation, which is part of Protein modification
Product Categories/Family for ST3GAL1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,075 Da
NCBI Official Full Name
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
NCBI Official Synonym Full Names
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
NCBI Official Symbol
ST3GAL1
NCBI Official Synonym Symbols
ST3O; SIAT4A; SIATFL; ST3GalA; ST3GalIA; Gal-NAc6S; ST3GalA.1; ST3GalIA,1
NCBI Protein Information
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; SIAT4-A; ST3GalI; alpha 2,3-ST 1; beta-galactoside alpha-2,3-sialyltransferase 1; sialyltransferase 4A (beta-galactosidase alpha-2,3
UniProt Protein Name
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
UniProt Gene Name
ST3GAL1
UniProt Synonym Gene Names
SIAT4; SIAT4A; Alpha 2,3-ST 1; Beta-galactoside alpha-2,3-sialyltransferase 1; ST3GalI; SIAT4-A
UniProt Entry Name
SIA4A_HUMAN
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Product Notes
The ST3GAL1 st3gal1 (Catalog #AAA849851) is a Recombinant Protein produced from Insect cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ST3Gal1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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