Immunohistochemistry (IHC)
(Immunochemical staining of human STARD5 in human kidney with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human STARD5 Polyclonal Antibody | anti-STARD5 antibody
Anti-STARD5 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
STARD5; Polyclonal Antibody; Anti-STARD5 Antibody; Rabbit Polyclonal; STARD5 Antibody; Rabbit PAb; Antigen Affinity Purified; StAR-related lipid transfer (START) domain containing 5; anti-STARD5 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human STARD5
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-STARD5 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:200-1:1000
Immunogen
E Coli-derived Human STARD5 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human STARD5 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human STARD5 in human kidney with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human STARD5 in human kidney with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human STARD5 in human liver with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human STARD5 in human liver with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-STARD5 antibody
STARD5 is a member of the STARD4 subfamily of steroidogenic acute regulatory lipid transfer (START) domain-containing proteins specialized in the non-vesicular transport of lipids and sterols. In macrophages, StarD5 is found in the cytosol and maintains a loose association with the Golgi. StarD5 protein is mainly localized in the nucleus, and upon ER stress, it redistributes away from the nucleus, localizing prominently to the cytosol and membranes. Like StarD1 and StarD4, StarD5 is known to bind cholesterol. The StarD4 and StarD5 proteins share approximately 30% identity, and each is a steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domain. STARD5 is a cytosolic sterol transport protein that is predominantly expressed in the liver and kidney. StarD5 is a stress-responsive protein that regulates PM cholesterol and intracellular cholesterol homeostasis.
References
Rodriguez-Agudo D, et al. (2012) Er stress increases stard5 expression by stabilizing its mrna and leads to relocalization of its protein from the nucleus to the membranes. J Lipid Res 53 (12): 2708-2715.Rodriguez-Agudo D, et al. (2006) Localization of stard5 cholesterol binding protein. J Lipid Res 47 (6): 1168-1175.Letourneau D, et al. (2013) Thermodynamic and solution state nmr characterization of the binding of secondary and conjugated bile acids to stard5. Biochim Biophys Acta 1831 (11): 1589-1599.
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Product Notes
The STARD5 (Catalog #AAA8110201) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-STARD5 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STARD5 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:200-1:1000. Researchers should empirically determine the suitability of the STARD5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STARD5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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