Porcine Aldehyde dehydrogenase family 1 member A3 ELISA Kit | ALDH1A3 elisa kit
Porcine Aldehyde dehydrogenase family 1 member A3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Uniprot Description
ALDH1A3: Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system. Belongs to the aldehyde dehydrogenase family.
Protein type: Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - phenylalanine; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Oxidoreductase; EC 1.2.1.5; Xenobiotic Metabolism - metabolism by cytochrome P450; Amino Acid Metabolism - histidine; Carbohydrate Metabolism - glycolysis and gluconeogenesis
Chromosomal Location of Human Ortholog: 15q26.3
Cellular Component: cytoplasm; cytosol
Molecular Function: aldehyde dehydrogenase (NAD) activity; protein homodimerization activity; aldehyde dehydrogenase [NAD(P)+] activity; retinal dehydrogenase activity
Biological Process: inner ear morphogenesis; retinal metabolic process; positive regulation of apoptosis; retinol metabolic process; righting reflex; embryonic eye morphogenesis; olfactory pit development; optic cup morphogenesis involved in camera-type eye development; retinoic acid metabolic process; locomotory behavior; neuromuscular process controlling balance; nucleus accumbens development
Disease: Microphthalmia, Isolated 8
Research Articles on ALDH1A3
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Product Notes
The Porcine ALDH1A3 aldh1a3 (Catalog #AAA747169) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA747169 ELISA Kit recognizes Porcine ALDH1A3. It is sometimes possible for the material contained within the vial of "Aldehyde dehydrogenase family 1 member A3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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