STAT3 Control Cell Extracts Immunoglobulin
STAT3 Control Cell Extracts (Signal Transducer and Activator of Transcription 3, Acute-phase Response Factor, APRF)
Purity
Lysate
Synonyms
STAT3 Control Cell Extracts; STAT3 Control Cell Extracts (Signal Transducer and Activator of Transcription 3; Acute-phase Response Factor; APRF); STAT3 Control Cell Extracts immunoglobulin
Purity/Purification
Lysate
Form/Format
Supplied as a liquid in SDS Sample Buffer: 62.5 Tris-HCl, pH 6.8 at 25 degree C, 2% w/v SDS, 10% glycerol, 50mM DTT, 0.01% w/v bromophenol blue.
Preparation and Storage
-20 degree C
Related Product Information for STAT3 Control Cell Extracts immunoglobulin
Stat3 is a key signaling molecule for many cytokines and growth-factor receptors (1) and is required for murine fetal development (2). Additionally, Stat3 is constitutively activated in a number of human tumors (3,4) and possesses oncogenic potential (5) and anti-apoptotic activities (3). Stat3 is activated by tyrosine phosphorylation at Tyr705, which induces dimerization, nuclear translocation and DNA binding (6,7). Transcriptional activation seems to be regulated by serine phosphorylation at Ser727, apparently via the MAPK or mTOR pathways (8,9). Stat3 isoform expression appears to reflect biological function: the relative expression levels of Stat3alpha (86kD) and Stat3beta (79kD) depend on cell type, ligand exposure or maturation stage of the cells (10). It is notable that Stat3beta lacks the serine phosphorylation site within the C-terminal transcriptional activation domain (8).
Product Categories/Family for STAT3 Control Cell Extracts immunoglobulin
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Product Notes
The STAT3 Control Cell Extracts (Catalog #AAA652619) is an Immunoglobulin and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "STAT3 Control Cell Extracts, Immunoglobulin" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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