Western Blot (WB)
(SP8 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SP8 antibody detected the SP8 protein (arrow).)
Rabbit SP8 Polyclonal Antibody | anti-SP8 antibody
SP8 Antibody (C-term)
Western Blot (WB)
(SP8 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SP8 antibody detected the SP8 protein (arrow).)
Western Blot (WB)
(SP8 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SP8 antibody detected the SP8 protein (arrow).)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :
Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)
Milona, M.A., et al. BMC Genomics 5 (1), 86 (2004) :
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an SP family transcription factor that in mouse has been shown to be essential for proper limb development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Uniprot Description
SP8: Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos. Belongs to the Sp1 C2H2-type zinc-finger protein family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 7p21.2
Cellular Component: nucleus
Molecular Function: DNA binding; metal ion binding
Biological Process: dorsal/ventral pattern formation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; proximal/distal pattern formation; embryonic limb morphogenesis
Research Articles on SP8
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Product Notes
The SP8 sp8 (Catalog #AAA9203908) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 386-415. The SP8 Antibody (C-term) reacts with Human, mouse (Predicted Reactivity: Chicken, Zebrafish, Xenopus) and may cross-react with other species as described in the data sheet. AAA Biotech's SP8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SP8 sp8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SP8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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