Immunohistochemistry (IHC)
(Immunohistochemical analysis of FHOD3 in formalin-fixed, paraffin-embedded mouse brain tissue using an isotype control (top left) and MBS644790(bottom, right) at 15ug/ml.)
Rabbit FHOD3 Polyclonal Antibody | anti-FHOD3 antibody
FHOD3 (FH1/FH2 Domain-containing Protein 3, Formactin-2, Formin Homolog Overexpressed in Spleen 2, hFHOS2, FHOS2, KIAA1695)
Gene Names
FHOD3; FHOS2; Formactin2
Reactivity
Bovine, Canine, Chicken, Equine, Human, Mouse
Applications
Immunohistochemistry
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
FHOD3; Polyclonal Antibody; FHOD3 (FH1/FH2 Domain-containing Protein 3; Formactin-2; Formin Homolog Overexpressed in Spleen 2; hFHOS2; FHOS2; KIAA1695); Anti -FHOD3 (FH1/FH2 Domain-containing Protein 3; anti-FHOD3 antibody
Host
Rabbit
Reactivity
Bovine, Canine, Chicken, Equine, Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human FHOD3. Species Crossreactivity: chicken, canine, equine, bovine, mouse, opossum.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Applicable Applications for anti-FHOD3 antibody
Immunohistochemistry (IHC)
Application Notes
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (formalin fixed paraffin embedded): 15ug/ml
Dilution: Immunohistochemistry (formalin fixed paraffin embedded): 15ug/ml
Immunogen
Synthetic peptide corresponding to aa1250-1300 of human FHOD3 (CRA_d).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunohistochemistry (IHC)
(Immunohistochemical analysis of FHOD3 in formalin-fixed, paraffin-embedded mouse brain tissue using an isotype control (top left) and MBS644790(bottom, right) at 15ug/ml.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of FHOD3 in formalin-fixed, paraffin-embedded mouse brain tissue using an isotype control (top left) and MBS644790(bottom, right) at 15ug/ml.)
Related Product Information for anti-FHOD3 antibody
FHOD3 is a novel member of the formin homology family playing an important role in regulation of the actin cytoskeleton. It contains aDD (diaphanous auto regulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. FHOD3 is a cytoplasmic protein where the main part of the protein localizes to actin fibers and the remaining part displays filamentous staining. FHOD3 is a 1422aa containing formin-related actin-organizing protein that may cause stress fiber formation together with cell elongation and may associate with nestin/NES-based interfilament (IF). Expression of FHOD3 is seen mainly in heart, kidney and brain.
Product Categories/Family for anti-FHOD3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
158,613 Da
NCBI Official Full Name
FH1/FH2 domain-containing protein 3 isoform 1
NCBI Official Synonym Full Names
formin homology 2 domain containing 3
NCBI Official Symbol
FHOD3
NCBI Official Synonym Symbols
FHOS2; Formactin2
NCBI Protein Information
FH1/FH2 domain-containing protein 3; hFHOS2; formactin-2; formin homolog overexpressed in spleen 2
UniProt Protein Name
FH1/FH2 domain-containing protein 3
Protein Family
UniProt Gene Name
FHOD3
UniProt Synonym Gene Names
FHOS2; KIAA1695; hFHOS2
UniProt Entry Name
FHOD3_HUMAN
NCBI Description
Proteins that contain formin (FMN1; MIM 136535) homology (FH) domains, such as FHOD3, play a role in regulation of the actin cytoskeleton (Kanaya et al., 2005 [PubMed 15966898]).[supplied by OMIM, Apr 2010]
Uniprot Description
FHOD3: Actin-organizing protein that may cause stress fiber formation together with cell elongation. Belongs to the formin homology family. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 18q12
Cellular Component: Z disc; striated muscle thin filament
Molecular Function: protein binding; actin binding
Biological Process: negative regulation of actin filament polymerization; actin filament network formation; cardiac myofibril assembly; sarcomere organization
Research Articles on FHOD3
Similar Products
Product Notes
The FHOD3 fhod3 (Catalog #AAA644790) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FHOD3 (FH1/FH2 Domain-containing Protein 3, Formactin-2, Formin Homolog Overexpressed in Spleen 2, hFHOS2, FHOS2, KIAA1695) reacts with Bovine, Canine, Chicken, Equine, Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FHOD3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Suitable for use in Immunohistochemistry. Dilution: Immunohistochemistry (formalin fixed paraffin embedded): 15ug/ml. Researchers should empirically determine the suitability of the FHOD3 fhod3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FHOD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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