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Western Blot (WB) (Western blot analysis of DAAM2 in human skeletal muscle lysate in the 1) absence, 2) presence of immunizing peptide and 3) mouse skeletal muscle lysate using MBS644750 at 0.5ug/ml.)

Rabbit anti-Human, Mouse DAAM2 Polyclonal Antibody | anti-DAAM2 antibody

DAAM2 (Disheveled-associated Activator Of Morphogenesis 2, KIAA0381)

Gene Names
DAAM2; dJ90A20A.1; RP1-278E11.1
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Affinity Purified
Purified by immunoaffinity chromatography.
Synonyms
DAAM2; Polyclonal Antibody; DAAM2 (Disheveled-associated Activator Of Morphogenesis 2; KIAA0381); Anti -DAAM2 (Disheveled-associated Activator Of Morphogenesis 2; anti-DAAM2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human DAAM2. Species Crossreactivity: mouse.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Applicable Applications for anti-DAAM2 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Dilution: Western Blot: 0.5-1ug/ml
Immunogen
Synthetic peptide corresponding to aa150-200 of human DAAM2.
Positive Control
Skeletal muscle lysate
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of DAAM2 in human skeletal muscle lysate in the 1) absence, 2) presence of immunizing peptide and 3) mouse skeletal muscle lysate using MBS644750 at 0.5ug/ml.)

Western Blot (WB) (Western blot analysis of DAAM2 in human skeletal muscle lysate in the 1) absence, 2) presence of immunizing peptide and 3) mouse skeletal muscle lysate using MBS644750 at 0.5ug/ml.)
Related Product Information for anti-DAAM2 antibody
DAAM2 is a recently identified planar cell polarity (PCP) signaling molecule implicated in the regulation of cellular polarity, convergent extension, and invasion. DAM2 belongs to the formin homology family and contains aDD (diaphanous autoregulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/ formin homology 3) domain. The DAM2 protein is known to be involved in cell divison. Though the exact function of DAM2 is yet unknown, reports suggest that it is closely related to DAM1 and hence along with DAM1 it may also be required in Wnt/Fz signaling and activation of Rho and in regulating cytoskeleton architecture. It is expressed in most of tissues but the expression level is higher in brain.
Product Categories/Family for anti-DAAM2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
123,499 Da
NCBI Official Full Name
disheveled-associated activator of morphogenesis 2 isoform 1
NCBI Official Synonym Full Names
dishevelled associated activator of morphogenesis 2
NCBI Official Symbol
DAAM2
NCBI Official Synonym Symbols
dJ90A20A.1; RP1-278E11.1
NCBI Protein Information
disheveled-associated activator of morphogenesis 2; dishevelled-associated activator of morphogenesis 2
UniProt Protein Name
Disheveled-associated activator of morphogenesis 2
UniProt Gene Name
DAAM2
UniProt Synonym Gene Names
KIAA0381
UniProt Entry Name
DAAM2_HUMAN

Uniprot Description

DAAM2: Belongs to the formin homology family.

Chromosomal Location of Human Ortholog: 6p21.2

Molecular Function: Rho GTPase binding; actin binding

Biological Process: actin cytoskeleton organization and biogenesis; determination of left/right symmetry

Research Articles on DAAM2

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Product Notes

The DAAM2 daam2 (Catalog #AAA644750) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DAAM2 (Disheveled-associated Activator Of Morphogenesis 2, KIAA0381) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DAAM2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 0.5-1ug/ml. Researchers should empirically determine the suitability of the DAAM2 daam2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DAAM2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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