Western Blot (WB)
(TXNDC5 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TXNDC5 antibody detected the TXNDC5 protein (arrow).)
Rabbit anti-Human TXNDC5 Polyclonal Antibody | anti-TXNDC5 antibody
TXNDC5, ID (TXNDC5, TLP46, Thioredoxin domain-containing protein 5, Endoplasmic reticulum resident protein 46, Thioredoxin-like protein p46) (AP)
Gene Names
TXNDC5; ERP46; HCC-2; STRF8; PDIA15; UNQ364; ENDOPDI
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
TXNDC5; Polyclonal Antibody; ID (TXNDC5; TLP46; Thioredoxin domain-containing protein 5; Endoplasmic reticulum resident protein 46; Thioredoxin-like protein p46) (AP); Thioredoxin-like protein p46; anti-TXNDC5 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-TXNDC5 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
TXNDC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-155 amino acids from the Central region of human TXNDC5.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(TXNDC5 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TXNDC5 antibody detected the TXNDC5 protein (arrow).)
Western Blot (WB)
(TXNDC5 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TXNDC5 antibody detected the TXNDC5 protein (arrow).)
Related Product Information for anti-TXNDC5 antibody
This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene.
Product Categories/Family for anti-TXNDC5 antibody
References
Zhang, L., et al. J. Cancer Res. Clin. Oncol. 136(10):1497-1505(2010). Jeong, K.H., et al. Br. J. Dermatol. 162(4):759-764(2010). Charlton, H.K., et al. Biochem. Biophys. Res. Commun. 392(2):234-239(2010). So, H.C., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (1), 103-113 (2010): Jessop, C.E., et al. J. Cell. Sci. 122 (PT 23), 4287-4295 (2009).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,629 Da
NCBI Official Full Name
thioredoxin domain-containing protein 5 isoform 3
NCBI Official Synonym Full Names
thioredoxin domain containing 5 (endoplasmic reticulum)
NCBI Official Symbol
TXNDC5
NCBI Official Synonym Symbols
ERP46; HCC-2; STRF8; PDIA15; UNQ364; ENDOPDI
NCBI Protein Information
thioredoxin domain-containing protein 5; ER protein 46; thioredoxin related protein; thioredoxin-like protein p46; endoplasmic reticulum protein ERp46; endothelial protein disulphide isomerase; endoplasmic reticulum resident protein 46; protein disulfide
UniProt Protein Name
Thioredoxin domain-containing protein 5
Protein Family
UniProt Gene Name
TXNDC5
UniProt Synonym Gene Names
TLP46; ER protein 46; ERp46
UniProt Entry Name
TXND5_HUMAN
NCBI Description
This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene. [provided by RefSeq, Dec 2010]
Uniprot Description
TXNDC5: Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast. Belongs to the protein disulfide isomerase family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 6p24.3
Cellular Component: lysosomal lumen; endoplasmic reticulum; endoplasmic reticulum lumen
Molecular Function: protein binding; protein disulfide isomerase activity
Biological Process: protein folding; cell redox homeostasis; post-Golgi vesicle-mediated transport; apoptotic cell clearance; negative regulation of apoptosis
Research Articles on TXNDC5
Similar Products
Product Notes
The TXNDC5 txndc5 (Catalog #AAA6360354) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TXNDC5, ID (TXNDC5, TLP46, Thioredoxin domain-containing protein 5, Endoplasmic reticulum resident protein 46, Thioredoxin-like protein p46) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TXNDC5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TXNDC5 txndc5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TXNDC5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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