Western Blot (WB)
(Western Blot: Sample: Mouse Cerebrum lysate; Primary Ab: 3ug/ml Rabbit Anti-Mouse PEBP1 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;)
Rabbit anti-Mouse Phosphatidylethanolamine Binding Protein 1 Polyclonal Antibody | anti-PEBP1 antibody
Polyclonal Antibody to Phosphatidylethanolamine Binding Protein 1 (PEBP1)
Immunohistochemistry: 5-20ug/mL;1:15-65
Immunocytochemistry: 5-20ug/mL;1:15-65
Optimal working dilutions must be determined by end user.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Mouse Cerebrum lysate; Primary Ab: 3ug/ml Rabbit Anti-Mouse PEBP1 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;)
Western Blot (WB)
(Western Blot: Sample: Mouse Cerebrum lysate; Primary Ab: 3ug/ml Rabbit Anti-Mouse PEBP1 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Mouse Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Mouse Tissue))
NCBI and Uniprot Product Information
Uniprot Description
RKIP: a metastasis suppressor that regulates extracellular matrix remodeling and tumor survival. Binds to and inhibits Raf-1. Phosphorylation by classic and atypical but not novel PKC isoforms dissociates this complex, relieving inhibition of the Raf/MAP kinase signaling cascade. Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. Cleaved into hippocampal cholinergic neurostimulating peptide (HCMP) that appears to be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Expressed in brain. Increased expression in aged senescence-accelerated mice.
Protein type: Lipid-binding; Protein kinase, regulatory subunit
Chromosomal Location of Human Ortholog: 5 F|5 56.88 cM
Cellular Component: apical part of cell; axon terminus; cell soma; cell surface; cytoplasm; extracellular exosome; extracellular space; Golgi apparatus; mitochondrial outer membrane; mitochondrion; myelin sheath; neuron projection; nucleus; rough endoplasmic reticulum; synaptic vesicle
Molecular Function: ATP binding; enzyme binding; kinase binding; lipid binding; mitogen-activated protein kinase binding; nucleotide binding; peptidase inhibitor activity; protein kinase binding; receptor binding; RNA binding; serine-type endopeptidase inhibitor activity
Biological Process: MAPK cascade; negative regulation of MAPKKK cascade; negative regulation of peptidase activity; negative regulation of protein phosphorylation; positive regulation of mitotic nuclear division; regulation of neurotransmitter levels; regulation of the force of heart contraction; sperm capacitation
Research Articles on PEBP1
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Product Notes
The PEBP1 pebp1 (Catalog #AAA2027049) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Phosphatidylethanolamine Binding Protein 1 (PEBP1) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Phosphatidylethanolamine Binding Protein 1 can be used in a range of immunoassay formats including, but not limited to, WB; IHC; ICC; IP. Western blotting: 0.5-2ug/mL;1:150-650 Immunohistochemistry: 5-20ug/mL;1:15-65 Immunocytochemistry: 5-20ug/mL;1:15-65 Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the PEBP1 pebp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Phosphatidylethanolamine Binding Protein 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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