Immunohistochemistry (IHC)
(Immunochemical staining of human GCDFP15 in human trachea with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections).)
Rabbit anti-Human PIP/GCDFP 15 Polyclonal Antibody | anti-PIP antibody
Anti-PIP/GCDFP 15 Antibody, Rabbit Polyclonal
Gene Names
PIP; GPIP4; GCDFP15; GCDFP-15
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
PIP/GCDFP 15; Polyclonal Antibody; Anti-PIP/GCDFP 15 Antibody; Rabbit Polyclonal; GCDFP-15 Antibody; Rabbit PAb; Antigen Affinity Purified; prolactin-induced protein; Anti-GCDFP-15 Antibody; Anti-GCDFP15 Antibody; Anti-GPIP4 Antibody; anti-PIP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human PIP
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-PIP antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:2500-1:10,000
Immunogen
A synthetic peptide corresponding to the N-terminus of the human GCDFP-15
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with A synthetic peptide corresponding to the N-terminus of the human GCDFP-15, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human GCDFP15 in human trachea with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining of human GCDFP15 in human trachea with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining of human GCDFP15 in human breast carcinoma with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining of human GCDFP15 in human breast carcinoma with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-PIP antibody
Prolactin-induced protein (PIP) is a small secreted glycoprotein carrying several N-linked carbohydrate chains. The expression of PIP is generally restricted to cells with apocrine properties. It was found in the apocrine glands of the axilla, vulva, eyelid, ear canal, and seminal vesicle. Being a secretory protein, PIP is present in seminal plasma, saliva, lacrimal fluid, tears, sweat gland secretion. The available data suggest that PIP can have immunomodulatory functions and plays an important role in cell-mediated adoptive immunity. PIP binds to bacteria from several genera, which suggests that this glycoprotein may participate also in innate immunity and protection of hosts against microbial infections. Increased levels of PIP were found in several types of human cancer (prostate, sweat, and salivary gland cancers). It is especially common in breast cancer, however, data on the expression of PIP in normal and cancerous breast cancer tissues are to some degree conflicting.
References
Urbaniak A, et al. (2018) Prolactin-induced protein (pip)-characterization and role in breast cancer progression. Am J Cancer Res 8 (11): 2150-2164.Gangadharan A, et al. (2018) Prolactin induced protein (pip) is a potential biomarker for early stage and malignant breast cancer. Breast 39 101-109.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16,572 Da
NCBI Official Full Name
prolactin-inducible protein
NCBI Official Synonym Full Names
prolactin-induced protein
NCBI Official Symbol
PIP
NCBI Official Synonym Symbols
GPIP4; GCDFP15; GCDFP-15
NCBI Protein Information
prolactin-inducible protein; SABP; secretory actin-binding protein; gross cystic disease fluid protein 15
UniProt Protein Name
Prolactin-inducible protein
Protein Family
UniProt Gene Name
PIP
UniProt Synonym Gene Names
GCDFP15; GPIP4; GCDFP-15; SABP
UniProt Entry Name
PIP_HUMAN
Uniprot Description
PIP: Belongs to the PIP family.
Protein type: Secreted; Cytoskeletal; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 7q34
Cellular Component: extracellular space; apical plasma membrane; nucleus
Molecular Function: protein dimerization activity; protein binding; IgG binding; actin binding; glycoprotein binding; aspartic-type endopeptidase activity
Biological Process: retinal homeostasis; regulation of immune system process; detection of chemical stimulus involved in sensory perception of bitter taste; proteolysis
Research Articles on PIP
Similar Products
Product Notes
The PIP pip (Catalog #AAA8100244) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PIP/GCDFP 15 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PIP/GCDFP 15 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:2500-1:10,000. Researchers should empirically determine the suitability of the PIP pip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIP/GCDFP 15, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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