Rabbit anti-Human Zinc Transporter ZIP2 Polyclonal Antibody | anti-SLC39A2 antibody
Anti-Zinc Transporter ZIP2 (Solute Carrier Family 39 Member 2, Zrt- and Irt-like Protein 2, ZIP-2, hZIP2, SLC39A2, 6A1, Eti-1, ZIP2)
Gene Names
SLC39A2; 6A1; ZIP2; Eti-1; ZIP-2; MGC119190
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
Zinc Transporter ZIP2; Polyclonal Antibody; Anti-Zinc Transporter ZIP2 (Solute Carrier Family 39 Member 2; Zrt- and Irt-like Protein 2; ZIP-2; hZIP2; SLC39A2; 6A1; Eti-1; ZIP2); Solute Carrier Family 39 Member 2; ZIP2; anti-SLC39A2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human ZIP2. Species sequence homology: mouse (84%).
Purity/Purification
Affinity Purified
Form/Format
Supplied as a liquid in PBS, 0.1% BSA.
Concentration
~1mg/ml (varies by lot)
Applicable Applications for anti-SLC39A2 antibody
ELISA; Western Blot; Immunohistochemistry
Application Notes
Suitable for use in Western Blot, ELISA, and Immunohistochemistry.
Recommended Dilutions: Western Blot: 1-10ug/ml (Chemiluminescence)
ELISA: 1:100,000
Immunohistochemistry: 2-10ug/ml
Recommended Dilutions: Western Blot: 1-10ug/ml (Chemiluminescence)
ELISA: 1:100,000
Immunohistochemistry: 2-10ug/ml
Immunogen
Synthetic peptide corresponding to 19aa of human ZIP2 (Accession #AAI13770), N-terminal, Extracellular domain (KLH).
Source Information
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Temperature: Blue Ice
Shipping Temperature: Blue Ice
Related Product Information for anti-SLC39A2 antibody
Zinc is an essential nutrient for all organisms because of the many important roles this metal plays. Movement of zinc into and out of cells and subcellular organelles is mediated by zinc transporter proteins. In many organisms, zinc uptake is mediated by members of the ZIP family of metal ion transporters. In mammals, the Zip1, Zip2, Zip3, Zip4, Zip5, LIV- 1 (Zip6), KE4 (Zip7), and BIGM103 (Zip8) proteins have been implicated in zinc uptake in a variety of cell and tissue types.
ZIP2 ((SLC39A2; Eti-1; 6A1)) encodes a protein of 309aa, includes an amino terminal signal peptide of 26aa, and has the predicted topology of Zip proteins. The human or mouse Zip2 overexpression in transfected K562 and human embryonic kidney (HEK293) cells, respectively, increased 65Zn uptake in these cells. hZIP2-induced Zn uptake was shown to be highly inhibited by Mn2+ and Co2+, metals that did not substantially affect hZIP1-, mZIP1-, or mZIP2-induced Zn uptake. Zn uptake mediated by hZIP2 appears to be stimulated by HCO 3, non-ATP dependent, but sensitive to N-ethylmaleimide, a sulfhydryl-reactive agent.
ZIP2 ((SLC39A2; Eti-1; 6A1)) encodes a protein of 309aa, includes an amino terminal signal peptide of 26aa, and has the predicted topology of Zip proteins. The human or mouse Zip2 overexpression in transfected K562 and human embryonic kidney (HEK293) cells, respectively, increased 65Zn uptake in these cells. hZIP2-induced Zn uptake was shown to be highly inhibited by Mn2+ and Co2+, metals that did not substantially affect hZIP1-, mZIP1-, or mZIP2-induced Zn uptake. Zn uptake mediated by hZIP2 appears to be stimulated by HCO 3, non-ATP dependent, but sensitive to N-ethylmaleimide, a sulfhydryl-reactive agent.
Product Categories/Family for anti-SLC39A2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,742 Da
NCBI Official Full Name
zinc transporter ZIP2
NCBI Official Synonym Full Names
solute carrier family 39 (zinc transporter), member 2
NCBI Official Symbol
SLC39A2
NCBI Official Synonym Symbols
6A1; ZIP2; Eti-1; ZIP-2; MGC119190
NCBI Protein Information
zinc transporter ZIP2; OTTHUMP00000164402; Zrt- and Irt-like protein 2; solute carrier family 39 member 2
UniProt Protein Name
Zinc transporter ZIP2
Protein Family
UniProt Gene Name
SLC39A2
UniProt Synonym Gene Names
ZIP2
UniProt Entry Name
S39A2_HUMAN
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Product Notes
The SLC39A2 slc39a2 (Catalog #AAA630429) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Zinc Transporter ZIP2 (Solute Carrier Family 39 Member 2, Zrt- and Irt-like Protein 2, ZIP-2, hZIP2, SLC39A2, 6A1, Eti-1, ZIP2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Zinc Transporter ZIP2 can be used in a range of immunoassay formats including, but not limited to, ELISA; Western Blot; Immunohistochemistry. Suitable for use in Western Blot, ELISA, and Immunohistochemistry. Recommended Dilutions: Western Blot: 1-10ug/ml (Chemiluminescence) ELISA: 1:100,000 Immunohistochemistry: 2-10ug/ml. Researchers should empirically determine the suitability of the SLC39A2 slc39a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Zinc Transporter ZIP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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