Immunohistochemistry (IHC)
(IHC of Formalin fixed paraffin embedded Human breast carcinoma using MBS618279.)
Rabbit anti-Human Jagged2 Polyclonal Antibody | anti-JAG2 antibody
Jagged2 (JAG2, HJ2)
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Dilution: ELISA: 1:500
Immunohistochemistry: 1:25-1:50
Immunohistochemistry (IHC)
(IHC of Formalin fixed paraffin embedded Human breast carcinoma using MBS618279.)
Immunohistochemistry (IHC)
(IHC of Formalin fixed paraffin embedded Human breast carcinoma using MBS618279.)
NCBI and Uniprot Product Information
NCBI Description
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Uniprot Description
JAG2: Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development. Expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Cell surface
Chromosomal Location of Human Ortholog: 14q32
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: protein binding; growth factor activity; calcium ion binding; Notch binding
Biological Process: regulation of cell adhesion; thymic T cell selection; Notch signaling pathway; in utero embryonic development; Notch receptor processing; cell cycle; regulation of cell migration; regulation of cell proliferation; odontogenesis of dentine-containing teeth; respiratory system process; morphogenesis of embryonic epithelium; spermatogenesis; cell differentiation; auditory receptor cell fate commitment; skeletal development; gamma-delta T cell differentiation; T cell differentiation
Research Articles on JAG2
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Product Notes
The JAG2 jag2 (Catalog #AAA618279) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Jagged2 (JAG2, HJ2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Jagged2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC). Suitable for use in ELISA and Immunohistochemistry. Dilution: ELISA: 1:500 Immunohistochemistry: 1:25-1:50. Researchers should empirically determine the suitability of the JAG2 jag2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Jagged2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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