Human Jagged 2 Protein (JAG2) ELISA Kit | JAG2 elisa kit

Human Jagged 2 Protein (JAG2) ELISA Kit

Cat. Num. AAA2020116

• Gene Names: JAG2; HJ2; SER2
• Reactivity: Human
• Synonyms: Jagged 2 Protein (JAG2); Human Jagged 2 Protein (JAG2) ELISA Kit; HJ2; JAG2 elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of JAG2. No significant cross-reactivity or interference between JAG2 and analogues was observed.
• Sequence Length: 180

• Samples: human serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids
• Detection Range: 0.312-20ng/mL
• Sensitivity: <0.113ng/mL
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level JAG2 were tested 20 times on one plate, respectively. Intra-Assay: CV<10%
• Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level JAG2 were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%
• Preparation and Storage: The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. ; To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for JAG2 elisa kit

Intended Uses: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of JAG2 in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Product Categories/Family for JAG2 elisa kit

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 62088320
• NCBI GeneID: 3714
• UniProt Accession #: Q9Y219; Q9UE17; Q9UE99; Q9UNK8; Q9Y6P9; Q9Y6Q0
• Molecular Weight: 129,235 Da
• NCBI Official Full Name: jagged 2 isoform b variant, partial
• NCBI Official Synonym Full Names: jagged 2
• NCBI Official Symbol: JAG2
• NCBI Official Synonym Symbols: HJ2; SER2
• NCBI Protein Information: protein jagged-2
• UniProt Protein Name: Protein jagged-2
• Protein Family: Protein jagged
• UniProt Gene Name: JAG2
• UniProt Synonym Gene Names: Jagged2; hJ2
• UniProt Entry Name: JAG2_HUMAN

NCBI Description

The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

JAG2: Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development. Expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q32

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: protein binding; growth factor activity; calcium ion binding; Notch binding

Biological Process: regulation of cell adhesion; thymic T cell selection; Notch signaling pathway; in utero embryonic development; Notch receptor processing; cell cycle; regulation of cell migration; regulation of cell proliferation; odontogenesis of dentine-containing teeth; respiratory system process; morphogenesis of embryonic epithelium; spermatogenesis; cell differentiation; auditory receptor cell fate commitment; skeletal development; T cell differentiation; gamma-delta T cell differentiation