Sheep anti Human IgA Secondary Antibody | IgA secondary antibody
Sheep anti Human IgA
Reactivity
Human
Applications
Immunodiffusion, Western Blot
Synonyms
Sheep anti Human IgA; Polyclonal Human IgA; Anti-Human IgA; Immunoglobulin A; IgA secondary antibody
Host
Sheep
Reactivity
Human
Specificity
Human
Form/Format
Supplied as a liquid in GBS.
Sequence Length
449
Applicable Applications for IgA secondary antibody
ODD, Immunodiffusion, Western Blot (WB)
Application Notes
ODD: 10 uL antiserum vs 10 uL Milk
WB: 100 uL antiserum vs 10 uL Milk
Immunodiffusion: 16 uL antiserum/cm^2 in gel vs 5 uL Milk, dilutions: Neat - 1:15.
WB: 100 uL antiserum vs 10 uL Milk
Immunodiffusion: 16 uL antiserum/cm^2 in gel vs 5 uL Milk, dilutions: Neat - 1:15.
Biological Significance
The secretory piece is a component of immunoglobulin A which consists of a portion of the polymeric immunoglobulin receptor. Polymeric IgA binds to the polymeric immunoglobulin receptor on the basolateral surface of epithelial cells and is taken up into the cell via transcytosis. The receptor-IgA complex passes through the cellular compartments before being secreted on the luminal surface of the epithelial cells, still attached to the receptor. Proteolysis of the receptor occurs and the dimeric IgA molecule, along with the secretory component, is free to diffuse throughout the lumen.
Immunogen
Human IgA antibody was raised in sheep using human secretory piece purified from human colostrum as the immunogen.
Preparation and Storage
Store at 4 degree C.
Related Product Information for IgA secondary antibody
Sheep anti Human IgA antibody
Product Categories/Family for IgA secondary antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
immunoglobulin A, partial
Protein Family
Similar Products
Product Notes
The IgA (Catalog #AAA535860) is a Secondary Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The Sheep anti Human IgA reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Sheep anti Human IgA can be used in a range of immunoassay formats including, but not limited to, ODD, Immunodiffusion, Western Blot (WB). ODD: 10 uL antiserum vs 10 uL Milk WB: 100 uL antiserum vs 10 uL Milk Immunodiffusion: 16 uL antiserum/cm^2 in gel vs 5 uL Milk, dilutions: Neat - 1:15. Researchers should empirically determine the suitability of the IgA for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Sheep anti Human IgA, Secondary Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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