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NKp46/NCR1/CD335 Recombinant Protein | NCR1 recombinant protein

Human CellExp NKp46/NCR1/CD335, Human Recombinant

Gene Names
NCR1; LY94; CD335; NKP46; NK-p46
Purity
>90%
Synonyms
NKp46/NCR1/CD335; Human CellExp NKp46/NCR1/CD335; Human Recombinant; NCR1; LY94; CD335; NK-p46; hNKp46; NCR1 recombinant protein
Ordering
For Research Use Only!
Host
HEK293 cells
Purity/Purification
>90%
Form/Format
Lyophilized powder. Lyophilized from 0.22um filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization
Sequence
Gln22-Asn254
Gene Source
Human
Reconstitution Instruction
Reconstitute in sterile deionized water to the desired protein concentration.
Tag Note
This protein carries a polyhistidine tag at the C-terminus.
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months

SDS-Page

SDS-Page
Related Product Information for NCR1 recombinant protein
Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1/CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34,481 Da
NCBI Official Full Name
natural cytotoxicity triggering receptor 1 isoform b
NCBI Official Synonym Full Names
natural cytotoxicity triggering receptor 1
NCBI Official Symbol
NCR1
NCBI Official Synonym Symbols
LY94; CD335; NKP46; NK-p46
NCBI Protein Information
natural cytotoxicity triggering receptor 1; NK cell-activating receptor; natural killer cell p46-related protein; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46)
UniProt Protein Name
Natural cytotoxicity triggering receptor 1
UniProt Gene Name
NCR1
UniProt Synonym Gene Names
LY94; NK-p46; NKp46; hNKp46
UniProt Entry Name
NCTR1_HUMAN

Uniprot Description

NCR1: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Belongs to the natural cytotoxicity receptor (NCR) family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Apoptosis; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: SWI/SNF complex; integral to plasma membrane

Molecular Function: receptor signaling protein activity

Biological Process: regulation of natural killer cell mediated cytotoxicity; cellular defense response; natural killer cell activation; signal transduction

Research Articles on NCR1

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Product Notes

The NCR1 ncr1 (Catalog #AAA8400106) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Gln22-Asn2 54. It is sometimes possible for the material contained within the vial of "NKp46/NCR1/CD335, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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